A family of pore-forming effector proteins that cause membrane permeabilization and PYROPTOSIS.. Gasdermin-induced pyroptosis plays a prominent role in many HEREDITARY DISEASES and autoinflammatory disorders as well as in CANCER.
Entry Term(s)
Cancer Associated Gasdermin-Domain Containing (GSDMDC) Proteins
A family of pore-forming effector proteins that cause membrane permeabilization and PYROPTOSIS.. Gasdermin-induced pyroptosis plays a prominent role in many HEREDITARY DISEASES and autoinflammatory disorders as well as in CANCER.