Sodium Channels MeSH Descriptor Data 2025

MeSH Heading: Sodium Channels
Tree Number(s): D12.776.157.530.400.875; D12.776.543.550.450.875; D12.776.543.585.400.875
Unique ID: D015222
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015222
Annotation: general or unspecified; prefer specifics
Scope Note: Ion channels that specifically allow the passage of SODIUM ions. A variety of specific sodium channel subtypes are involved in serving specialized functions such as neuronal signaling, CARDIAC MUSCLE contraction, and KIDNEY function.
Entry Version: NA CHANNELS
Entry Term(s): Ion Channel, Sodium; Ion Channels, Sodium; Sodium Channel; Sodium Ion Channels
Registry Numbers: 0
Previous Indexing: Ion Channels (1979-1988); Sodium (1979-1988)
See Also: Sodium-Potassium-Exchanging ATPase
Public MeSH Note: 89
History Note: 89
Entry Combination: agonists:Sodium Channel Agonists; antagonists & inhibitors:Sodium Channel Blockers
Date Established: 1989/01/01
Date of Entry: 1988/05/12
Revision Date: 2016/07/01

Entry Combination: agonists:Sodium Channel Agonists; antagonists & inhibitors:Sodium Channel Blockers
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Calcium Channels [D12.776.157.530.400.150]
        
        Channelrhodopsins [D12.776.157.530.400.163]
        
        Chloride Channels [D12.776.157.530.400.175]
        
        Cyclic Nucleotide-Gated Cation Channels [D12.776.157.530.400.337]
        
        Gasdermins [D12.776.157.530.400.353]
        
        Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels [D12.776.157.530.400.368]
        
        Ligand-Gated Ion Channels [D12.776.157.530.400.400]
        
        Porins [D12.776.157.530.400.500]
        
        Potassium Channels [D12.776.157.530.400.600]
        
        Sodium Channels [D12.776.157.530.400.875]
        
        Acid Sensing Ion Channels [D12.776.157.530.400.875.050]
        
        Degenerin Sodium Channels [D12.776.157.530.400.875.100]
        
        Epithelial Sodium Channels [D12.776.157.530.400.875.200]
        
        Voltage-Gated Sodium Channels [D12.776.157.530.400.875.750]
        
        Transient Receptor Potential Channels [D12.776.157.530.400.901]
        
        Two-Pore Channels [D12.776.157.530.400.950]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Calcium Channels [D12.776.543.550.450.150]
        
        Channelrhodopsins [D12.776.543.550.450.163]
        
        Chloride Channels [D12.776.543.550.450.175]
        
        Cyclic Nucleotide-Gated Cation Channels [D12.776.543.550.450.452]
        
        Gasdermins [D12.776.543.550.450.464]
        
        Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels [D12.776.543.550.450.476]
        
        Ligand-Gated Ion Channels [D12.776.543.550.450.500]
        
        Porins [D12.776.543.550.450.730]
        
        Potassium Channels [D12.776.543.550.450.750]
        
        Sodium Channels [D12.776.543.550.450.875]
        
        Acid Sensing Ion Channels [D12.776.543.550.450.875.050]
        
        Degenerin Sodium Channels [D12.776.543.550.450.875.100]
        
        Epithelial Sodium Channels [D12.776.543.550.450.875.200]
        
        Voltage-Gated Sodium Channels [D12.776.543.550.450.875.750]
        
        Two-Pore Channels [D12.776.543.550.450.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Calcium Channels [D12.776.543.585.400.150]
        
        Channelrhodopsins [D12.776.543.585.400.163]
        
        Chloride Channels [D12.776.543.585.400.175]
        
        Cyclic Nucleotide-Gated Cation Channels [D12.776.543.585.400.452]
        
        Gasdermins [D12.776.543.585.400.464]
        
        Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels [D12.776.543.585.400.476]
        
        Ligand-Gated Ion Channels [D12.776.543.585.400.500]
        
        Porins [D12.776.543.585.400.730]
        
        Potassium Channels [D12.776.543.585.400.750]
        
        Sodium Channels [D12.776.543.585.400.875]
        
        Acid Sensing Ion Channels [D12.776.543.585.400.875.050]
        
        Degenerin Sodium Channels [D12.776.543.585.400.875.100]
        
        Epithelial Sodium Channels [D12.776.543.585.400.875.200]
        
        Voltage-Gated Sodium Channels [D12.776.543.585.400.875.750]
        
        Transient Receptor Potential Channels [D12.776.543.585.400.901]
        
        Two-Pore Channels [D12.776.543.585.400.950]

Sodium Channels Preferred

Concept UI: M0023385
Registry Numbers: 0
Scope Note: Ion channels that specifically allow the passage of SODIUM ions. A variety of specific sodium channel subtypes are involved in serving specialized functions such as neuronal signaling, CARDIAC MUSCLE contraction, and KIDNEY function.
Terms: Sodium Channels Preferred Term
Term UI T044527
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1989); Ion Channel, Sodium
Term UI T044523
Date02/17/1993
LexicalTag NON
ThesaurusID NLM (1994); Sodium Ion Channels
Term UI T044524
Date04/15/1993
LexicalTag NON
ThesaurusID NLM (1994); Ion Channels, Sodium
Term UI T044525
Date05/12/1988
LexicalTag NON
ThesaurusID UNK (19XX); Sodium Channel
Term UI T044526
Date02/17/1993
LexicalTag NON
ThesaurusID NLM (1994)

page delivered in 0.15s