MeSH Browser

MeSH Heading: Fibronectins
Tree Number(s): D09.400.430.890.350; D12.776.377.715.390; D12.776.395.550.350; D12.776.543.550.350; D12.776.860.300.450
Unique ID: D005353
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005353
Annotation: extracellular matrix proteins; /‌biosyn /‌physiol permitted
Scope Note: Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.
Entry Term(s): Cold-Insoluble Globulins; Fibronectin; LETS Proteins; Opsonic Glycoprotein; Opsonic alpha(2)SB Glycoprotein; alpha 2-Surface Binding Glycoprotein
NLM Classification #: QU 55.3
Previous Indexing: Cryoglobulins (1966-1979); Glycoproteins (1966-1979); Membrane Proteins (1977-1979)
See Also: Receptors, Fibronectin
Public MeSH Note: 80
History Note: 80
Date Established: 1980/01/01
Date of Entry: 1979/02/21
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0008450
Scope Note: Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.
Terms: Fibronectins Preferred Term
Term UI T016341
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1980); Opsonic alpha(2)SB Glycoprotein
Term UI T016342
Date01/20/1982
LexicalTag NON
ThesaurusID UNK (19XX); Fibronectin
Term UI T016340
Date12/18/1981
LexicalTag NON
ThesaurusID UNK (19XX); LETS Proteins
Term UI T016344
Date02/21/1979
LexicalTag NON
ThesaurusID UNK (19XX); alpha 2-Surface Binding Glycoprotein
Term UI T016345
Date03/14/1980
LexicalTag NON
ThesaurusID UNK (19XX); Opsonic Glycoprotein
Term UI T016346
Date02/10/1981
LexicalTag NON
ThesaurusID UNK (19XX); Cold-Insoluble Globulins
Term UI T016343
Date02/21/1979
LexicalTag NON
ThesaurusID UNK (19XX)

Fibronectins MeSH Descriptor Data 2025