MeSH Browser

MeSH Heading: Triggering Receptor Expressed on Myeloid Cells-1
Tree Number(s): D09.400.430.890.919; D12.776.395.550.919; D12.776.543.550.919; D12.776.543.750.705.985
Unique ID: D000073871
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000073871
Scope Note: An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
Entry Term(s): CD354 Antigen; TREM-1 Protein
Previous Indexing: Membrane Glycoproteins (2000-2017); Receptors, Immunologic (2000-2017)
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Lymphocyte Activation Gene 3 Protein [D12.776.543.750.705.012]
        
        Leukocyte Immunoglobulin-like Receptor B1 [D12.776.543.750.705.023]
        
        Lipopolysaccharide Receptors [D12.776.543.750.705.045]
        
        Costimulatory and Inhibitory T-Cell Receptors [D12.776.543.750.705.222]
        
        Immunophilins [D12.776.543.750.705.400]
        
        Integrins [D12.776.543.750.705.408]
        
        Platelet Membrane Glycoproteins [D12.776.543.750.705.675]
        
        Receptors, Antigen [D12.776.543.750.705.816]
        
        Receptors, Complement [D12.776.543.750.705.833]
        
        Receptors, Cytokine [D12.776.543.750.705.852]
        
        Receptors, Fc [D12.776.543.750.705.871]
        
        Receptors, Formyl Peptide [D12.776.543.750.705.873]
        
        Receptors, Laminin [D12.776.543.750.705.876]
        
        Receptors, Lymphocyte Homing [D12.776.543.750.705.877]
        
        Receptors, Mitogen [D12.776.543.750.705.880]
        
        Receptors, Natural Killer Cell [D12.776.543.750.705.895]
        
        Receptors, Pattern Recognition [D12.776.543.750.705.910]
        
        Receptors, Scavenger [D12.776.543.750.705.940]
        
        Signaling Lymphocytic Activation Molecule Family [D12.776.543.750.705.970]
        
        Triggering Receptor Expressed on Myeloid Cells-1 [D12.776.543.750.705.985]

Triggering Receptor Expressed on Myeloid Cells-1 Preferred

Concept UI: M000624135
Scope Note: An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
Terms: Triggering Receptor Expressed on Myeloid Cells-1 Preferred Term
Term UI T000912289
Date11/29/2016
LexicalTag NON
ThesaurusID NLM (2018); CD354 Antigen
Term UI T000912290
Date11/29/2016
LexicalTag ABX
ThesaurusID NLM (2018); TREM-1 Protein
Term UI T000912291
Date11/29/2016
LexicalTag ACX
ThesaurusID NLM (2018)

Triggering Receptor Expressed on Myeloid Cells-1 MeSH Descriptor Data 2025