MeSH Browser

MeSH Heading: Fertilins
Tree Number(s): D08.811.277.656.675.374.102.750; D09.400.430.500.750; D09.400.430.890.331; D12.776.395.033.750; D12.776.395.550.331
Unique ID: D000072196
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072196
Scope Note: Sperm surface proteins involved in sperm-egg fusion. They consist of two subunits, fertilin alpha (ADAM1a) and beta (ADAM2), both of which belong to the metalloprotease-disintegrin protein family. The beta subunit does not have catalytic activity.
Entry Term(s): ADAM 1a Protein; ADAM 2 Protein; ADAM1 Protein; ADAM1a Protein; ADAM2 Protein; Fertilin; Fertilin Protein; Fertilin alpha; Fertilin beta; PH 30 Fusion Protein; PH-30 Fusion Protein; PH-30 Protein; PH-30 alpha; PH-30 beta
Public MeSH Note: 2017; FERTILINS was indexed under ADAM PROTEINS and MEMBRANE GLYCOPROTEINS 2006-2016; and under METALLOENDOPEPTIDASES 1992-2005
History Note: 2017 (1992)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0199142
Scope Note: Sperm surface proteins involved in sperm-egg fusion. They consist of two subunits, fertilin alpha (ADAM1a) and beta (ADAM2), both of which belong to the metalloprotease-disintegrin protein family. The beta subunit does not have catalytic activity.
Terms: Fertilins Preferred Term
Term UI T000900447
Date05/06/2016
LexicalTag NON
ThesaurusID NLM (2017); Fertilin Protein
Term UI T000898449
Date04/07/2016
LexicalTag NON
ThesaurusID NLM (2017); Fertilin
Term UI T000898437
Date04/07/2016
LexicalTag NON
ThesaurusID NLM (1992); PH 30 Fusion Protein
Term UI T000898438
Date04/07/2016
LexicalTag ABX
ThesaurusID NLM (1992); PH-30 Fusion Protein
Term UI T000898439
Date04/07/2016
LexicalTag ABX
ThesaurusID NLM (1992); PH-30 Protein
Term UI T000898440
Date04/07/2016
LexicalTag ABX
ThesaurusID NLM (2017)

Concept UI: M0199136
Terms: Fertilin alpha Preferred Term
Term UI T000900448
Date05/06/2016
LexicalTag NON
ThesaurusID NLM (2017); ADAM1 Protein
Term UI T000898451
Date04/07/2016
LexicalTag ACX
ThesaurusID NLM (1992); ADAM1a Protein
Term UI T000898453
Date04/07/2016
LexicalTag ACX
ThesaurusID NLM (2017); ADAM 1a Protein
Term UI T000898454
Date04/07/2016
LexicalTag ACX
ThesaurusID NLM (2017); PH-30 alpha
Term UI T000900449
Date05/06/2016
LexicalTag ABX
ThesaurusID NLM (2017)

Concept UI: M0199137
Terms: Fertilin beta Preferred Term
Term UI T000900450
Date05/06/2016
LexicalTag NON
ThesaurusID NLM (2017); ADAM2 Protein
Term UI T000898455
Date04/07/2016
LexicalTag ACX
ThesaurusID NLM (2017); PH-30 beta
Term UI T000900451
Date05/06/2016
LexicalTag ABX
ThesaurusID NLM (2017); ADAM 2 Protein
Term UI T000898442
Date04/07/2016
LexicalTag ACX
ThesaurusID NLM (2001)

Fertilins MeSH Descriptor Data 2025