MeSH Browser

MeSH Heading: ADAM12 Protein
Tree Number(s): D08.811.277.656.675.374.102.125; D09.400.430.500.125; D12.776.395.033.125
Unique ID: D000072199
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072199
Scope Note: A disintegrin and metalloproteinase domain-containing protein that is expressed as two alternatively-spliced forms: a long transmembrane form (ADAM12-L) and a short soluble form (ADAM12-S). It modulates the cleavage of INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS and may also regulate CELL FUSION during MYOGENESIS.
Entry Term(s): ADAM 12 Protein; ADAM-12 Protein; ADAM12-L Protein; ADAM12-S Protein; Disintegrin and Metalloproteinase Domain-Containing Protein 12; Meltrin-alpha Protein
Registry Numbers: EC 3.4.24.-; 0
Related Numbers: EC 3.4.24.82
Public MeSH Note: 2017; ADAM12 PROTEIN was indexed under MEMBRANE PROTEINS and ADAM PROTEINS 2006-2016; and under METALLOENDOPEPTIDASES 1997-2005
History Note: 2017 (1997)
Date Established: 2017/01/01
Date of Entry: 2016/07/06
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0272293
Registry Numbers: EC 3.4.24.-
Related Numbers: EC 3.4.24.82
Scope Note: A disintegrin and metalloproteinase domain-containing protein that is expressed as two alternatively-spliced forms: a long transmembrane form (ADAM12-L) and a short soluble form (ADAM12-S). It modulates the cleavage of INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS and may also regulate CELL FUSION during MYOGENESIS.
Terms: ADAM12 Protein Preferred Term
Term UI T000898495
Date04/07/2016
LexicalTag ACX
ThesaurusID NLM (2017); Disintegrin and Metalloproteinase Domain-Containing Protein 12
Term UI T000900380
Date05/04/2016
LexicalTag NON
ThesaurusID NLM (2017); ADAM-12 Protein
Term UI T000898493
Date04/07/2016
LexicalTag ACX
ThesaurusID NLM (2017); ADAM 12 Protein
Term UI T000898494
Date04/07/2016
LexicalTag ACX
ThesaurusID NLM (1997); Meltrin-alpha Protein
Term UI T000898497
Date04/07/2016
LexicalTag NON
ThesaurusID NLM (2017)

ADAM12 Protein MeSH Descriptor Data 2025