MeSH Browser

MeSH Heading: Mucin-1
Tree Number(s): D09.400.430.890.560; D09.400.430.900.631.115; D12.776.395.550.560; D12.776.395.560.631.115; D12.776.543.550.530; D23.050.285.050.300; D23.050.550.325.300; D23.101.140.075.300
Unique ID: D018396
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018396
Scope Note: Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.
Entry Term(s): Antigen CA-15-3; Antigens, CD227; CA 15-3 Antigen; CA 15.3 Antigen; CA-15-3 Antigen; CD227 Antigen; Episialin; Epithelial Membrane Antigen; Epithelial Mucin, Polymorphic; Muc1 Mucin; Polymorphic Epithelial Mucin
Previous Indexing: Antigens, Neoplasm (1986-1988); Antigens, Tumor-Associated, Carbohydrate (1989-1994)
Public MeSH Note: 2009; see CA-15-3 ANTIGEN 1995-2008, see ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE 1990-1994; EPISIALIN was indexed under MEMBRANE GLYCOPROTEINS 1988-1996, MUCINS 1981-1996, MEMBRANE PROTEINS 1982-1987, & GLYCOPROTEINS 1981-1982
History Note: 2009(1995)
Date Established: 1995/01/01
Date of Entry: 1994/04/16
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Mucoproteins [D09.400.430.900]
      - Mucins [D09.400.430.900.631]
        
        CA-125 Antigen [D09.400.430.900.631.050]
        
        Gastric Mucins [D09.400.430.900.631.100]
        
        Mucin-1 [D09.400.430.900.631.115]
        
        Mucin-2 [D09.400.430.900.631.161]
        
        Mucin-3 [D09.400.430.900.631.184]
        
        Mucin-4 [D09.400.430.900.631.195]
        
        Mucin-5B [D09.400.430.900.631.207]
        
        Sialomucins [D09.400.430.900.631.650]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Mucoproteins [D12.776.395.560]
      - Mucins [D12.776.395.560.631]
        
        CA-125 Antigen [D12.776.395.560.631.050]
        
        Gastric Mucins [D12.776.395.560.631.100]
        
        Mucin-1 [D12.776.395.560.631.115]
        
        Mucin-2 [D12.776.395.560.631.161]
        
        Mucin-3 [D12.776.395.560.631.184]
        
        Mucin-4 [D12.776.395.560.631.195]
        
        Mucin-5B [D12.776.395.560.631.207]
        
        Sialomucins [D12.776.395.560.631.650]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Neoplasm [D23.050.285]
    - Antigens, Tumor-Associated, Carbohydrate [D23.050.285.050]

Biological Factors [D23]
- Antigens [D23.050]
  - Epitopes [D23.050.550]
    - Antigens, Tumor-Associated, Carbohydrate [D23.050.550.325]

Biological Factors [D23]
- Biomarkers [D23.101]
  - Biomarkers, Tumor [D23.101.140]
    - Antigens, Tumor-Associated, Carbohydrate [D23.101.140.075]

Mucin-1 Preferred

Concept UI: M0027622
Scope Note: Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.
Terms: Mucin-1 Preferred Term
Term UI T716321
Date03/14/2008
LexicalTag NON
ThesaurusID NLM (2009); Epithelial Mucin, Polymorphic
Term UI T054853
Date11/08/1995
LexicalTag NON
ThesaurusID NLM (1997); Polymorphic Epithelial Mucin
Term UI T054854
Date11/08/1995
LexicalTag NON
ThesaurusID NLM (1997); Epithelial Membrane Antigen
Term UI T054855
Date11/08/1995
LexicalTag NON
ThesaurusID NLM (1997); Muc1 Mucin
Term UI T054856
Date11/08/1995
LexicalTag NON
ThesaurusID NLM (1997); Antigens, CD227
Term UI T716322
Date03/14/2008
LexicalTag ABX
ThesaurusID NLM (2009); CD227 Antigen
Term UI T716323
Date03/14/2008
LexicalTag ABX
ThesaurusID NLM (2009); CA 15-3 Antigen
Term UI T054848
Date09/15/1993
LexicalTag NON
ThesaurusID NLM (1995); CA 15.3 Antigen
Term UI T054849
Date09/15/1993
LexicalTag NON
ThesaurusID NLM (1995); Antigen CA-15-3
Term UI T054850
Date01/26/1994
LexicalTag NON
ThesaurusID NLM (1995); Episialin
Term UI T054852
Date11/08/1995
LexicalTag NON
ThesaurusID NLM (1997); CA-15-3 Antigen
Term UI T054851
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1995)

Mucin-1 MeSH Descriptor Data 2025