MeSH Browser

MeSH Heading: Variant Surface Glycoproteins, Trypanosoma
Tree Number(s): D09.400.430.890.990; D12.776.395.550.990; D12.776.543.550.990; D12.776.820.125.900; D23.050.293.900; D23.050.301.900
Unique ID: D014643
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D014643
Scope Note: Glycoproteins attached to the surface coat of the trypanosome. Many of these glycoproteins show amino acid sequence diversity expressed as antigenic variations. This continuous development of antigenically distinct variants in the course of infection ensures that some trypanosomes always survive the development of immune response to propagate the infection.
Entry Version: VSG TRYPAN
Entry Term(s): SSP-4; Surface Variant Glycoproteins, Trypanosoma; Trypanosoma Variant Surface Coat Glycoproteins; VSG 117; VSG 118; VSG 221
Previous Indexing: Glycoproteins (1966-1987); Membrane Proteins (1977-1987)
Public MeSH Note: 88
History Note: 88
Date Established: 1988/01/01
Date of Entry: 1987/05/05
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0022522
Scope Note: Glycoproteins attached to the surface coat of the trypanosome. Many of these glycoproteins show amino acid sequence diversity expressed as antigenic variations. This continuous development of antigenically distinct variants in the course of infection ensures that some trypanosomes always survive the development of immune response to propagate the infection.
Terms: Variant Surface Glycoproteins, Trypanosoma Preferred Term
Term UI T042834
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1988); SSP-4
Term UI T042831
Date06/09/1989
LexicalTag ABB
ThesaurusID NLM (1990); Trypanosoma Variant Surface Coat Glycoproteins
Term UI T042832
Date05/05/1987
LexicalTag NON
ThesaurusID UNK (19XX); Surface Variant Glycoproteins, Trypanosoma
Term UI T042833
Date05/05/1987
LexicalTag NON
ThesaurusID UNK (19XX)

Variant Surface Glycoproteins, Trypanosoma MeSH Descriptor Data 2025