MeSH Browser

MeSH Heading: Fas Ligand Protein
Tree Number(s): D09.400.430.890.312; D12.644.276.374.750.249; D12.776.395.550.312; D12.776.467.374.750.249; D12.776.543.550.312; D23.529.374.750.249
Unique ID: D053222
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053222
Scope Note: A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.
Entry Term(s): Antigens, CD178; CD178 Antigen; CD178 Antigens; CD95 Antigen Ligand; CD95 Ligand; CD95L; Fas Ligand; Fas Ligand (FasL); FasL Protein; TNF Superfamily, Member 6; Tumor Necrosis Factor Ligand Superfamily Member 6
Public MeSH Note: 2007; FAS LIGAND PROTEIN was indexed under TUMOR NECROSIS FACTORS and MEMBRANE GLYCOPROTEINS 1994-2006
History Note: 2007(1994)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intercellular Signaling Peptides and Proteins [D12.644.276]
    - Cytokines [D12.644.276.374]
      - Tumor Necrosis Factors [D12.644.276.374.750]
        
        CD27 Ligand [D12.644.276.374.750.030]
        
        B-Cell Activating Factor [D12.644.276.374.750.061]
        
        4-1BB Ligand [D12.644.276.374.750.065]
        
        CD30 Ligand [D12.644.276.374.750.092]
        
        CD40 Ligand [D12.644.276.374.750.124]
        
        Cytokine TWEAK [D12.644.276.374.750.155]
        
        Ectodysplasins [D12.644.276.374.750.186]
        
        Fas Ligand Protein [D12.644.276.374.750.249]
        
        Lymphotoxin-alpha [D12.644.276.374.750.500]
        
        Lymphotoxin alpha1, beta2 Heterotrimer [D12.644.276.374.750.505]
        
        Lymphotoxin-beta [D12.644.276.374.750.515]
        
        OX40 Ligand [D12.644.276.374.750.531]
        
        RANK Ligand [D12.644.276.374.750.562]
        
        TNF-Related Apoptosis-Inducing Ligand [D12.644.276.374.750.625]
        
        Tumor Necrosis Factor-alpha [D12.644.276.374.750.626]
        
        Tumor Necrosis Factor Ligand Superfamily Member 13 [D12.644.276.374.750.656]
        
        Tumor Necrosis Factor Ligand Superfamily Member 14 [D12.644.276.374.750.690]
        
        Tumor Necrosis Factor Ligand Superfamily Member 15 [D12.644.276.374.750.720]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intercellular Signaling Peptides and Proteins [D12.776.467]
    - Cytokines [D12.776.467.374]
      - Tumor Necrosis Factors [D12.776.467.374.750]
        
        CD27 Ligand [D12.776.467.374.750.030]
        
        B-Cell Activating Factor [D12.776.467.374.750.061]
        
        4-1BB Ligand [D12.776.467.374.750.065]
        
        CD30 Ligand [D12.776.467.374.750.092]
        
        CD40 Ligand [D12.776.467.374.750.124]
        
        Cytokine TWEAK [D12.776.467.374.750.155]
        
        Ectodysplasins [D12.776.467.374.750.186]
        
        Fas Ligand Protein [D12.776.467.374.750.249]
        
        Lymphotoxin-alpha [D12.776.467.374.750.500]
        
        Lymphotoxin alpha1, beta2 Heterotrimer [D12.776.467.374.750.505]
        
        Lymphotoxin-beta [D12.776.467.374.750.515]
        
        OX40 Ligand [D12.776.467.374.750.531]
        
        RANK Ligand [D12.776.467.374.750.562]
        
        TNF-Related Apoptosis-Inducing Ligand [D12.776.467.374.750.625]
        
        Tumor Necrosis Factor-alpha [D12.776.467.374.750.626]
        
        Tumor Necrosis Factor Ligand Superfamily Member 13 [D12.776.467.374.750.656]
        
        Tumor Necrosis Factor Ligand Superfamily Member 14 [D12.776.467.374.750.690]
        
        Tumor Necrosis Factor Ligand Superfamily Member 15 [D12.776.467.374.750.710]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]

Biological Factors [D23]
- Intercellular Signaling Peptides and Proteins [D23.529]
  - Cytokines [D23.529.374]
    - Tumor Necrosis Factors [D23.529.374.750]

Fas Ligand Protein Preferred

Concept UI: M0229054
Scope Note: A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.
Terms: Fas Ligand Protein Preferred Term
Term UI T665167
Date01/27/2006
LexicalTag NON
ThesaurusID NLM (2007); Tumor Necrosis Factor Ligand Superfamily Member 6
Term UI T661551
Date12/07/2005
LexicalTag NON
ThesaurusID NLM (2007); CD178 Antigens
Term UI T664881
Date01/23/2006
LexicalTag ABX
ThesaurusID NLM (2007); CD95 Antigen Ligand
Term UI T259055
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); CD95L
Term UI T259056
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (2007); Fas Ligand (FasL)
Term UI T259057
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); FasL Protein
Term UI T259059
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); TNF Superfamily, Member 6
Term UI T660200
Date11/28/2005
LexicalTag ABX
ThesaurusID NLM (2007); CD95 Ligand
Term UI T660203
Date11/28/2005
LexicalTag ABX
ThesaurusID NLM (2007); CD178 Antigen
Term UI T660206
Date11/28/2005
LexicalTag ABX
ThesaurusID NLM (2007); Fas Ligand
Term UI T660208
Date11/28/2005
LexicalTag ABX
ThesaurusID NLM (2007); Antigens, CD178
Term UI T660207
Date11/28/2005
LexicalTag ABX
ThesaurusID NLM (2007)

Fas Ligand Protein MeSH Descriptor Data 2025