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Immunoglobulins MeSH Descriptor Data 2022


MeSH Heading
Immunoglobulins
Tree Number(s)
D12.776.124.486.485
D12.776.124.790.651
D12.776.377.715.548
Unique ID
D007136
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007136
Annotation
general: prefer specifics; /‌admin: consider also IMMUNOGLOBULINS, INTRAVENOUS; /‌defic permitted but consider also IMMUNOLOGIC DEFICIENCY SYNDROMES ; /‌ther use: consider also IMMUNOGLOBULIN THERAPY see IMMUNIZATION, PASSIVE; allotypes = IMMUNOGLOBULIN ALLOTYPES or specifics
Scope Note
Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.
Entry Term(s)
Globulins, Immune
Immune Globulin
Immune Globulins
Immunoglobulin
Pharm Action
Immunologic Factors
Registry Number
0
NLM Classification #
QW 601
Previous Indexing
Gamma Globulins (1966-1969)
See Also
Immunity
Paraproteinemias
Public MeSH Note
72; IMMUNE SERUM GLOBULIN was heading 1965; GLOBULINS, IMMUNE & IMMUNE GLOBULINS were see IMMUNOGLOBULINS, INTRAVENOUS 1992-93
Online Note
use IMMUNOGLOBULINS, INTRAVENOUS to search GLOBULINS, IMMUNE& IMMUNE GLOBULINS 1992-93
History Note
72(70); IMMUNE SERUM GLOBULIN was heading 1965; GLOBULINS, IMMUNE & IMMUNE GLOBULINS were see IMMUNOGLOBULINS, INTRAVENOUS 1992-93
Date Established
1972/01/01
Date of Entry
1999/01/01
Revision Date
2020/05/27
Immunoglobulins Preferred
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