MeSH Browser

MeSH Heading: Immunoglobulin Heavy Chains
Tree Number(s): D12.776.124.486.485.705.500; D12.776.124.790.651.705.500; D12.776.377.715.548.705.500
Unique ID: D007143
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007143
Annotation: gammopathy: coordinate IMMUNOGLOBULIN HEAVY CHAINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM) or HEAVY CHAIN DISEASE (IM), follow text
Scope Note: The largest of polypeptide chains comprising immunoglobulins. They contain 450 to 600 amino acid residues per chain, and have molecular weights of 51-72 kDa.
Entry Term(s): Heavy-Chain Immunoglobulins; Ig Heavy Chains; Immunoglobulin Heavy Chain; Immunoglobulin Heavy Chain Subgroup VH-I; Immunoglobulin Heavy Chain Subgroup VH-III; Immunoglobulins, Heavy-Chain
Pharm Action: Immunologic Factors
Previous Indexing: Immunoglobulin Fragments (1973-1974)
See Also: Heavy Chain Disease
Public MeSH Note: 2006; see IMMUNOGLOBULINS, HEAVY-CHAIN 1992-2005, see IMMUNOGLOBULINS, HEAVY CHAIN 1976-1991, see IMMUNOGLOBULIN FRAGMENTS 1973-1975
History Note: 2006 (1973)
Date Established: 1976/01/01
Date of Entry: 1999/01/01
Revision Date: 2019/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0011134
Scope Note: The largest of polypeptide chains comprising immunoglobulins. They contain 450 to 600 amino acid residues per chain, and have molecular weights of 51-72 kDa.
Terms: Immunoglobulin Heavy Chains Preferred Term
Term UI T633345
Date03/15/2005
LexicalTag NON
ThesaurusID NLM (2006); Heavy-Chain Immunoglobulins
Term UI T021396
Date01/01/1986
LexicalTag NON
ThesaurusID UNK (19XX); Immunoglobulin Heavy Chain
Term UI T021397
Date05/09/1987
LexicalTag NON
ThesaurusID NLM (1988); Immunoglobulins, Heavy-Chain
Term UI T021398
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Ig Heavy Chains
Term UI T643004
Date06/13/2005
LexicalTag NON
ThesaurusID NLM (2006)

Immunoglobulin Heavy Chains MeSH Descriptor Data 2025