MeSH Browser

MeSH Heading: Immunoglobulin mu-Chains
Tree Number(s): D12.776.124.486.485.114.619.574.500; D12.776.124.486.485.705.500.500; D12.776.124.790.651.114.619.574.500; D12.776.124.790.651.705.500.500; D12.776.377.715.548.114.619.574.500; D12.776.377.715.548.705.500.500
Unique ID: D007148
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007148
Annotation: gammopathy: coordinate IMMUNOGLOBULIN MU-CHAINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM) or HEAVY CHAIN DISEASE (IM), follow text; for immunoglobulin C mu (IG C mu) coordinate with IMMUNOGLOBULIN CONSTANT REGION
Scope Note: The class of heavy chains found in IMMUNOGLOBULIN M. They have a molecular weight of approximately 72 kDa and they contain about 57 amino acid residues arranged in five domains and have more oligosaccharide branches and a higher carbohydrate content than the heavy chains of IMMUNOGLOBULIN G.
Entry Version: IG MU CHAINS
Entry Term(s): Ig mu Chains; Immunoglobulin mu-Chain; Immunoglobulins, mu-Chain; mu Immunoglobulin Heavy Chain; mu Immunoglobulin Heavy Chains; mu-Chain Immunoglobulins
Pharm Action: Immunologic Factors
NLM Classification #: QW 601
Previous Indexing: IgM (1973-1975); Immunoglobulin Fragments (1973-1975); Immunoglobulins, Heavy Chain (1975)
Public MeSH Note: 2006; see IMMUNOGLOBULINS, MU-CHAIN 1992-2005, see IMMUNOGLOBULINS, MU CHAIN 1987-1991, see IMMUNOGLOBULINS, HEAVY CHAIN 1976-1986
History Note: 2006 (1976)
Date Established: 1987/01/01
Date of Entry: 1975/07/23
Revision Date: 2019/07/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Immunoproteins [D12.776.124.486]
      - Immunoglobulins [D12.776.124.486.485]
        
        Antibodies [D12.776.124.486.485.114]
        
        Immunoglobulin Isotypes [D12.776.124.486.485.114.619]
        
        Immunoglobulin M [D12.776.124.486.485.114.619.574]
        
        Immunoglobulin mu-Chains [D12.776.124.486.485.114.619.574.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Immunoproteins [D12.776.124.486]
      - Immunoglobulins [D12.776.124.486.485]
        
        Immunoglobulin Subunits [D12.776.124.486.485.705]
        
        Immunoglobulin Heavy Chains [D12.776.124.486.485.705.500]
        
        Immunoglobulin alpha-Chains [D12.776.124.486.485.705.500.350]
        
        Immunoglobulin delta-Chains [D12.776.124.486.485.705.500.360]
        
        Immunoglobulin epsilon-Chains [D12.776.124.486.485.705.500.370]
        
        Immunoglobulin gamma-Chains [D12.776.124.486.485.705.500.380]
        
        Immunoglobulin mu-Chains [D12.776.124.486.485.705.500.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Serum Globulins [D12.776.124.790]
      - Immunoglobulins [D12.776.124.790.651]
        
        Antibodies [D12.776.124.790.651.114]
        
        Immunoglobulin Isotypes [D12.776.124.790.651.114.619]
        
        Immunoglobulin M [D12.776.124.790.651.114.619.574]
        
        Immunoglobulin mu-Chains [D12.776.124.790.651.114.619.574.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Serum Globulins [D12.776.124.790]
      - Immunoglobulins [D12.776.124.790.651]
        
        Immunoglobulin Subunits [D12.776.124.790.651.705]
        
        Immunoglobulin Heavy Chains [D12.776.124.790.651.705.500]
        
        Immunoglobulin alpha-Chains [D12.776.124.790.651.705.500.350]
        
        Immunoglobulin delta-Chains [D12.776.124.790.651.705.500.360]
        
        Immunoglobulin epsilon-Chains [D12.776.124.790.651.705.500.370]
        
        Immunoglobulin gamma-Chains [D12.776.124.790.651.705.500.380]
        
        Immunoglobulin mu-Chains [D12.776.124.790.651.705.500.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Globulins [D12.776.377]
    - Serum Globulins [D12.776.377.715]
      - Immunoglobulins [D12.776.377.715.548]
        
        Antibodies [D12.776.377.715.548.114]
        
        Immunoglobulin Isotypes [D12.776.377.715.548.114.619]
        
        Immunoglobulin M [D12.776.377.715.548.114.619.574]
        
        Immunoglobulin mu-Chains [D12.776.377.715.548.114.619.574.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Globulins [D12.776.377]
    - Serum Globulins [D12.776.377.715]
      - Immunoglobulins [D12.776.377.715.548]
        
        Immunoglobulin Subunits [D12.776.377.715.548.705]
        
        Immunoglobulin Heavy Chains [D12.776.377.715.548.705.500]
        
        Immunoglobulin alpha-Chains [D12.776.377.715.548.705.500.350]
        
        Immunoglobulin delta-Chains [D12.776.377.715.548.705.500.360]
        
        Immunoglobulin epsilon-Chains [D12.776.377.715.548.705.500.370]
        
        Immunoglobulin gamma-Chains [D12.776.377.715.548.705.500.380]
        
        Immunoglobulin mu-Chains [D12.776.377.715.548.705.500.500]

Immunoglobulin mu-Chains Preferred

Concept UI: M0011144
Scope Note: The class of heavy chains found in IMMUNOGLOBULIN M. They have a molecular weight of approximately 72 kDa and they contain about 57 amino acid residues arranged in five domains and have more oligosaccharide branches and a higher carbohydrate content than the heavy chains of IMMUNOGLOBULIN G.
Terms: Immunoglobulin mu-Chains Preferred Term
Term UI T634115
Date03/23/2005
LexicalTag NON
ThesaurusID NLM (2006); mu-Chain Immunoglobulins
Term UI T021420
Date01/01/1986
LexicalTag NON
ThesaurusID UNK (19XX); Ig mu Chains
Term UI T000952313
Date03/01/2019
LexicalTag NON
ThesaurusID NLM (2020); Immunoglobulin mu-Chain
Term UI T634112
Date03/23/2005
LexicalTag NON
ThesaurusID NLM (2006); mu Immunoglobulin Heavy Chains
Term UI T634116
Date03/23/2005
LexicalTag NON
ThesaurusID NLM (2006); mu Immunoglobulin Heavy Chain
Term UI T634117
Date03/23/2005
LexicalTag NON
ThesaurusID NLM (2006); Immunoglobulins, mu-Chain
Term UI T021421
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1976)

Immunoglobulin mu-Chains MeSH Descriptor Data 2025