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Immunoglobulin Variable Region MeSH Descriptor Data 2023


MeSH Heading
Immunoglobulin Variable Region
Tree Number(s)
D12.644.541.500.650.500
D12.776.124.486.485.680.650.500
D12.776.124.486.485.797
D12.776.124.790.651.680.650.500
D12.776.124.790.651.797
D12.776.377.715.548.680.650.500
D12.776.377.715.548.797
G02.111.570.060.425
Unique ID
D007135
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007135
Scope Note
That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.
Entry Term(s)
Framework Region, Immunoglobulin
Fv Antibody Fragments
Fv Fragments
Ig Framework Region
Ig Variable Region
Immunoglobulin Framework Region
Immunoglobulin Fv Fragments
Immunoglobulin V
Variable Region, Ig
Variable Region, Immunoglobulin
Pharm Action
Immunologic Factors
Registry Number
0
Previous Indexing
Antigenic Determinants (1972-1976)
Binding Sites, Antibody (1973-1976)
Immunoglobulin Fragments (1973-1976)
Immunoglobulins, Fab (1973-1976)
See Also
Binding Sites, Antibody
Immunoglobulin Domains
Public MeSH Note
84; was see under BINDING SITES, ANTIBODY 1977-83
History Note
84(77); was see under BINDING SITES, ANTIBODY 1977-83
Date Established
1984/01/01
Date of Entry
1976/04/16
Revision Date
2015/11/20
Immunoglobulin Variable Region Preferred
Immunoglobulin Fv Fragments Related
Framework Region, Immunoglobulin Narrower
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