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Immunoglobulin Fab Fragments MeSH Descriptor Data 2023


MeSH Heading
Immunoglobulin Fab Fragments
Tree Number(s)
D12.644.541.500.650
D12.776.124.486.485.680.650
D12.776.124.790.651.680.650
D12.776.377.715.548.680.650
Unique ID
D007140
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007140
Scope Note
Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
Entry Version
IG FAB FRAGMENTS
Entry Term(s)
Fab Fragment
Fab Fragments
Fab Immunoglobulin Fragments
Ig Fab Fragments
Immunoglobulin Fab Fragment
Immunoglobulins, Fab
Immunoglobulins, Fab Fragment
Pharm Action
Immunologic Factors
Registry Number
0
Previous Indexing
Immunoglobulins (1970-1972)
Public MeSH Note
2006; was IMMUNOGLOBULINS, FAB 1973-2005
History Note
2006 (1973)
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2020/05/27
Immunoglobulin Fab Fragments Preferred
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