- Concept UI
- M0011127
- Scope Note
- Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
- Terms
-
Immunoglobulin Fc Fragments
Preferred Term
Term UI
T633966
Date03/22/2005
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Fc Fragment
Term UI
T001088269
Date09/08/2020
LexicalTag
NON
ThesaurusID
NLM (2022)
-
Ig Fc Fragments
Term UI
T000962318
Date06/25/2019
LexicalTag
ABX
ThesaurusID
NLM (2020)
-
Fc Fragments
Term UI
T021384
Date03/30/1974
LexicalTag
NON
ThesaurusID
UNK (19XX)
-
Fc Immunoglobulins
Term UI
T021385
Date03/18/1991
LexicalTag
NON
ThesaurusID
NLM (1992)
-
Immunoglobulin Fc Fragment
Term UI
T633967
Date03/22/2005
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Immunoglobulins, Fc
Term UI
T021386
Date01/01/1999
LexicalTag
ABX
ThesaurusID
NLM (1973)
-
Fc Immunoglobulin
Term UI
T001088268
Date09/08/2020
LexicalTag
NON
ThesaurusID
NLM (2022)
-
Immunoglobulins, Fc Fragment
Term UI
T634184
Date03/23/2005
LexicalTag
NON
ThesaurusID
NLM (2006)