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CD4 Immunoadhesins MeSH Descriptor Data 2025


MeSH Heading
CD4 Immunoadhesins
Tree Number(s)
D09.400.430.890.200.230
D12.644.541.500.697.249
D12.776.124.486.485.538.500.249
D12.776.124.486.485.680.697.249
D12.776.124.790.651.538.500.249
D12.776.124.790.651.680.660.249
D12.776.377.715.548.538.500.249
D12.776.377.715.548.680.660.249
D12.776.395.550.200.230
D12.776.543.550.200.230
D12.776.828.300.200
D23.050.301.350.230
Unique ID
D016860
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016860
Scope Note
Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of immunoglobulins. These have potential use in the therapy of AIDS since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and Fc receptor-binding functions of immunoglobulin.
Entry Term(s)
CD4-IgG
Immunoadhesins, CD4
Pharm Action
Immunologic Factors
Previous Indexing
Antigens, CD (1990-1991)
Antigens, Differentiation, T-Lymphocyte (1989)
IgG (1989-1991)
Public MeSH Note
92; CD4 IMMUNOADHESIN (NM) was indexed under IGG & ANTIGENS, CD & ANTIBODIES, ANTI-IDIOTYPIC 1990-91 and under ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1989.
Online Note
use CD4 IMMUNOADHESINS (NM) to search CD4 IMMUNOADHESIN (NM) 1989-91
History Note
92; was CD4 IMMUNOADHESIN (NM) 1989-91
Date Established
1992/01/01
Date of Entry
1991/07/12
Revision Date
2023/03/16
CD4 Immunoadhesins Preferred
CD4-IgG Narrower
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