Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of immunoglobulins. These have potential use in the therapy of AIDS since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and Fc receptor-binding functions of immunoglobulin.
92; CD4 IMMUNOADHESIN (NM) was indexed under IGG & ANTIGENS, CD & ANTIBODIES, ANTI-IDIOTYPIC 1990-91 and under ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1989.
Online Note
use CD4 IMMUNOADHESINS (NM) to search CD4 IMMUNOADHESIN (NM) 1989-91
Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of immunoglobulins. These have potential use in the therapy of AIDS since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and Fc receptor-binding functions of immunoglobulin.
