MeSH Browser

MeSH Heading: 12E7 Antigen
Tree Number(s): D12.776.395.550.200.049; D12.776.543.550.200.062; D23.050.301.350.049
Unique ID: D000071443
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071443
Scope Note: A cell adhesion molecule that, in humans, is encoded by a gene on the PSEUDOAUTOSOMAL REGION of SEX CHROMOSOMES. It functions in CELL ADHESION of T-LYMPHOCYTES and ROSETTE FORMATION by ERYTHROCYTES. It is also involved in the migration of LEUKOCYTES through the ENDOTHELIUM BASEMENT MEMBRANE. The 12E7 antigen co-localizes with, but functions independently of PECAM-1.
Entry Term(s): 12E7 Protein; Antigens, CD99; CD99 Antigen; CD99 Molecule; E2 Antigen; MIC2 Protein; T-Cell Surface Glycoprotein E2
Registry Number: 0
Previous Indexing: Antigens, CD (2004-2016); Cell Adhesion Molecules (2004-2016)
Public MeSH Note: 2018; see ANTIGENS, CD99 2017-2018
History Note: 2018 (2017)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Cell Adhesion Molecules [D12.776.395.550.200]
        
        12E7 Antigen [D12.776.395.550.200.049]
        
        CD11 Antigens [D12.776.395.550.200.074]
        
        CD24 Antigen [D12.776.395.550.200.098]
        
        Cell Adhesion Molecule-1 [D12.776.395.550.200.115]
        
        Nectins [D12.776.395.550.200.123]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D12.776.395.550.200.131]
        
        CD146 Antigen [D12.776.395.550.200.170]
        
        Endolyn [D12.776.395.550.200.175]
        
        Cadherin Related Proteins [D12.776.395.550.200.188]
        
        Cadherins [D12.776.395.550.200.200]
        
        Carcinoembryonic Antigen [D12.776.395.550.200.210]
        
        CD4 Immunoadhesins [D12.776.395.550.200.230]
        
        Cell Adhesion Molecules, Neuronal [D12.776.395.550.200.250]
        
        Epithelial Cell Adhesion Molecule [D12.776.395.550.200.263]
        
        Integrin alphaXbeta2 [D12.776.395.550.200.275]
        
        Intercellular Adhesion Molecule-1 [D12.776.395.550.200.450]
        
        Intercellular Adhesion Molecule-3 [D12.776.395.550.200.494]
        
        Junctional Adhesion Molecules [D12.776.395.550.200.537]
        
        Receptors, Lymphocyte Homing [D12.776.395.550.200.625]
        
        Selectins [D12.776.395.550.200.700]
        
        Sialic Acid Binding Ig-like Lectin 2 [D12.776.395.550.200.810]
        
        Vascular Cell Adhesion Molecule-1 [D12.776.395.550.200.920]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Cell Adhesion Molecules [D12.776.543.550.200]
        
        12E7 Antigen [D12.776.543.550.200.062]
        
        CD11 Antigens [D12.776.543.550.200.093]
        
        CD24 Antigen [D12.776.543.550.200.124]
        
        Cell Adhesion Molecule-1 [D12.776.543.550.200.128]
        
        Nectins [D12.776.543.550.200.130]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D12.776.543.550.200.131]
        
        CD146 Antigen [D12.776.543.550.200.140]
        
        Endolyn [D12.776.543.550.200.145]
        
        Cadherins [D12.776.543.550.200.200]
        
        Carcinoembryonic Antigen [D12.776.543.550.200.210]
        
        CD4 Immunoadhesins [D12.776.543.550.200.230]
        
        Cell Adhesion Molecules, Neuronal [D12.776.543.550.200.250]
        
        Epithelial Cell Adhesion Molecule [D12.776.543.550.200.263]
        
        Integrin alphaXbeta2 [D12.776.543.550.200.275]
        
        Intercellular Adhesion Molecule-1 [D12.776.543.550.200.450]
        
        Intercellular Adhesion Molecule-3 [D12.776.543.550.200.494]
        
        Junctional Adhesion Molecules [D12.776.543.550.200.537]
        
        Receptors, Lymphocyte Homing [D12.776.543.550.200.625]
        
        Selectins [D12.776.543.550.200.700]
        
        Sialic Acid Binding Ig-like Lectin 2 [D12.776.543.550.200.810]
        
        Vascular Cell Adhesion Molecule-1 [D12.776.543.550.200.920]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Cell Adhesion Molecules [D23.050.301.350]

12E7 Antigen Preferred

Concept UI: M000614695
Registry Number: 0
Scope Note: A cell adhesion molecule that, in humans, is encoded by a gene on the PSEUDOAUTOSOMAL REGION of SEX CHROMOSOMES. It functions in CELL ADHESION of T-LYMPHOCYTES and ROSETTE FORMATION by ERYTHROCYTES. It is also involved in the migration of LEUKOCYTES through the ENDOTHELIUM BASEMENT MEMBRANE. The 12E7 antigen co-localizes with, but functions independently of PECAM-1.
Terms: 12E7 Antigen Preferred Term
Term UI T000919401
Date03/20/2017
LexicalTag ABX
ThesaurusID NLM (2018); CD99 Molecule
Term UI T000895412
Date02/17/2016
LexicalTag ABX
ThesaurusID NLM (2017); 12E7 Protein
Term UI T000895414
Date02/17/2016
LexicalTag ABX
ThesaurusID NLM (2017); MIC2 Protein
Term UI T000895417
Date02/17/2016
LexicalTag ABX
ThesaurusID NLM (2017); Antigens, CD99
Term UI T000897307
Date03/18/2016
LexicalTag ABX
ThesaurusID NLM (2017); T-Cell Surface Glycoprotein E2
Term UI T000897308
Date03/18/2016
LexicalTag NON
ThesaurusID NLM (2017); CD99 Antigen
Term UI T000895411
Date02/17/2016
LexicalTag ABX
ThesaurusID NLM (2017); E2 Antigen
Term UI T000895415
Date02/17/2016
LexicalTag ABX
ThesaurusID NLM (2017)

12E7 Antigen MeSH Descriptor Data 2023