MeSH Browser

MeSH Heading: Integrin alphaXbeta2
Tree Number(s): D09.400.430.890.200.275; D12.776.395.550.200.275; D12.776.543.550.200.275; D12.776.543.750.705.408.600.100; D12.776.543.750.705.833.249; D23.050.301.350.275
Unique ID: D016167
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016167
Scope Note: A major adhesion-associated heterodimer molecule expressed by MONOCYTES; GRANULOCYTES; NK CELLS; and some LYMPHOCYTES. The alpha subunit is the CD11C ANTIGEN, a surface antigen expressed on some myeloid cells. The beta subunit is the CD18 ANTIGEN.
Entry Term(s): Antigen p150,95; CR4 Receptor; Complement Receptor 4; Complement Receptor Type 4; Leukocyte Adhesion Protein p150,95; Neutrophil GP150; Neutrophil Glycoprotein Gp150; Receptor, CR4; alphaXbeta2 Integrin; p150,95 Antigen; p150,95 Glycoprotein
Registry Numbers: 0
Previous Indexing: Antigens, Differentiation (1988-1990); Receptors, Leukocyte-Adhesion (1989-1990)
Public MeSH Note: 2003; see COMPLEMENT 4-BINDING PROTEIN 2002, see ANTIGEN P150,95 1991-2001; INTEGRIN APHAXBETA2 was indexed under MEMBRANE GLYCOPROTEINS 1988-2002 & GLYCOPROTEINS 1985-1987
History Note: 2003 (1991); use INTEGRIN ALPHAXBETA2 (NM) 1985-2002
Date Established: 1991/01/01
Date of Entry: 1990/04/24
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - Cell Adhesion Molecules [D09.400.430.890.200]
        
        12E7 Antigen [D09.400.430.890.200.049]
        
        CD11 Antigens [D09.400.430.890.200.074]
        
        CD24 Antigen [D09.400.430.890.200.098]
        
        CEACAM1 Protein [D09.400.430.890.200.107]
        
        Cell Adhesion Molecule-1 [D09.400.430.890.200.115]
        
        Nectins [D09.400.430.890.200.123]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D09.400.430.890.200.131]
        
        CD146 Antigen [D09.400.430.890.200.170]
        
        Endolyn [D09.400.430.890.200.175]
        
        Cadherin Related Proteins [D09.400.430.890.200.188]
        
        Cadherins [D09.400.430.890.200.200]
        
        Carcinoembryonic Antigen [D09.400.430.890.200.210]
        
        CD4 Immunoadhesins [D09.400.430.890.200.230]
        
        Cell Adhesion Molecules, Neuronal [D09.400.430.890.200.250]
        
        Epithelial Cell Adhesion Molecule [D09.400.430.890.200.263]
        
        Integrin alphaXbeta2 [D09.400.430.890.200.275]
        
        CD11c Antigen [D09.400.430.890.200.275.500]
        
        CD18 Antigens [D09.400.430.890.200.275.750]
        
        Intercellular Adhesion Molecule-1 [D09.400.430.890.200.450]
        
        Intercellular Adhesion Molecule-3 [D09.400.430.890.200.494]
        
        Junctional Adhesion Molecules [D09.400.430.890.200.537]
        
        Receptors, Lymphocyte Homing [D09.400.430.890.200.625]
        
        Selectins [D09.400.430.890.200.700]
        
        Sialic Acid Binding Ig-like Lectin 2 [D09.400.430.890.200.810]
        
        Vascular Cell Adhesion Molecule-1 [D09.400.430.890.200.920]
        
        Vasodilator-Stimulated Phosphoprotein [D09.400.430.890.200.960]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Cell Adhesion Molecules [D12.776.395.550.200]
        
        12E7 Antigen [D12.776.395.550.200.049]
        
        CD11 Antigens [D12.776.395.550.200.074]
        
        CD24 Antigen [D12.776.395.550.200.098]
        
        CEACAM1 Protein [D12.776.395.550.200.107]
        
        Cell Adhesion Molecule-1 [D12.776.395.550.200.115]
        
        Nectins [D12.776.395.550.200.123]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D12.776.395.550.200.131]
        
        CD146 Antigen [D12.776.395.550.200.170]
        
        Endolyn [D12.776.395.550.200.175]
        
        Cadherin Related Proteins [D12.776.395.550.200.188]
        
        Cadherins [D12.776.395.550.200.200]
        
        Carcinoembryonic Antigen [D12.776.395.550.200.210]
        
        CD4 Immunoadhesins [D12.776.395.550.200.230]
        
        Cell Adhesion Molecules, Neuronal [D12.776.395.550.200.250]
        
        Epithelial Cell Adhesion Molecule [D12.776.395.550.200.263]
        
        Integrin alphaXbeta2 [D12.776.395.550.200.275]
        
        CD11c Antigen [D12.776.395.550.200.275.500]
        
        CD18 Antigens [D12.776.395.550.200.275.750]
        
        Intercellular Adhesion Molecule-1 [D12.776.395.550.200.450]
        
        Intercellular Adhesion Molecule-3 [D12.776.395.550.200.494]
        
        Junctional Adhesion Molecules [D12.776.395.550.200.537]
        
        Receptors, Lymphocyte Homing [D12.776.395.550.200.625]
        
        Selectins [D12.776.395.550.200.700]
        
        Sialic Acid Binding Ig-like Lectin 2 [D12.776.395.550.200.810]
        
        Vascular Cell Adhesion Molecule-1 [D12.776.395.550.200.920]
        
        Vasodilator-Stimulated Phosphoprotein [D12.776.395.550.200.960]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Cell Adhesion Molecules [D12.776.543.550.200]
        
        12E7 Antigen [D12.776.543.550.200.062]
        
        CD11 Antigens [D12.776.543.550.200.093]
        
        CD24 Antigen [D12.776.543.550.200.124]
        
        CEACAM1 Protein [D12.776.543.550.200.126]
        
        Cell Adhesion Molecule-1 [D12.776.543.550.200.128]
        
        Nectins [D12.776.543.550.200.130]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D12.776.543.550.200.131]
        
        CD146 Antigen [D12.776.543.550.200.140]
        
        Endolyn [D12.776.543.550.200.145]
        
        Cadherins [D12.776.543.550.200.200]
        
        Carcinoembryonic Antigen [D12.776.543.550.200.210]
        
        CD4 Immunoadhesins [D12.776.543.550.200.230]
        
        Cell Adhesion Molecules, Neuronal [D12.776.543.550.200.250]
        
        Epithelial Cell Adhesion Molecule [D12.776.543.550.200.263]
        
        Integrin alphaXbeta2 [D12.776.543.550.200.275]
        
        CD11c Antigen [D12.776.543.550.200.275.500]
        
        CD18 Antigens [D12.776.543.550.200.275.750]
        
        Intercellular Adhesion Molecule-1 [D12.776.543.550.200.450]
        
        Intercellular Adhesion Molecule-3 [D12.776.543.550.200.494]
        
        Junctional Adhesion Molecules [D12.776.543.550.200.537]
        
        Receptors, Lymphocyte Homing [D12.776.543.550.200.625]
        
        Selectins [D12.776.543.550.200.700]
        
        Sialic Acid Binding Ig-like Lectin 2 [D12.776.543.550.200.810]
        
        Vascular Cell Adhesion Molecule-1 [D12.776.543.550.200.920]
        
        Vasodilator-Stimulated Phosphoprotein [D12.776.543.550.200.960]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Integrins [D12.776.543.750.705.408]
        
        Receptors, Leukocyte-Adhesion [D12.776.543.750.705.408.600]
        
        Integrin alphaXbeta2 [D12.776.543.750.705.408.600.100]
        
        CD11c Antigen [D12.776.543.750.705.408.600.100.500]
        
        CD18 Antigens [D12.776.543.750.705.408.600.100.750]
        
        Lymphocyte Function-Associated Antigen-1 [D12.776.543.750.705.408.600.400]
        
        Macrophage-1 Antigen [D12.776.543.750.705.408.600.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Complement [D12.776.543.750.705.833]
        
        CD11b Antigen [D12.776.543.750.705.833.062]
        
        Membrane Cofactor Protein [D12.776.543.750.705.833.124]
        
        Integrin alphaXbeta2 [D12.776.543.750.705.833.249]
        
        CD11c Antigen [D12.776.543.750.705.833.249.500]
        
        CD18 Antigens [D12.776.543.750.705.833.249.750]
        
        Macrophage-1 Antigen [D12.776.543.750.705.833.500]
        
        Receptor, Anaphylatoxin C5a [D12.776.543.750.705.833.550]
        
        Receptors, Complement 3b [D12.776.543.750.705.833.600]
        
        Receptors, Complement 3d [D12.776.543.750.705.833.610]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Cell Adhesion Molecules [D23.050.301.350]

Integrin alphaXbeta2 Preferred

Concept UI: M0024681
Registry Numbers: 0
Scope Note: A major adhesion-associated heterodimer molecule expressed by MONOCYTES; GRANULOCYTES; NK CELLS; and some LYMPHOCYTES. The alpha subunit is the CD11C ANTIGEN, a surface antigen expressed on some myeloid cells. The beta subunit is the CD18 ANTIGEN.
Terms: Integrin alphaXbeta2 Preferred Term
Term UI T417182
Date06/20/2000
LexicalTag NON
ThesaurusID NLM (2003); Antigen p150,95
Term UI T048004
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1991); Leukocyte Adhesion Protein p150,95
Term UI T048005
Date02/10/1990
LexicalTag NON
ThesaurusID NLM (1991); p150,95 Glycoprotein
Term UI T048006
Date02/10/1990
LexicalTag NON
ThesaurusID NLM (1991); Neutrophil GP150
Term UI T163584
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); Neutrophil Glycoprotein Gp150
Term UI T163585
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); alphaXbeta2 Integrin
Term UI T417181
Date06/20/2000
LexicalTag NON
ThesaurusID NLM (2003); Receptor, CR4
Term UI T429324
Date11/21/2000
LexicalTag ACX
ThesaurusID NLM (2002); CR4 Receptor
Term UI T452292
Date06/26/2001
LexicalTag NON
ThesaurusID NLM (2002); Complement Receptor 4
Term UI T488924
Date04/08/2002
LexicalTag NON
ThesaurusID NLM (2003); p150,95 Antigen
Term UI T048003
Date03/19/1990
LexicalTag NON
ThesaurusID NLM (1991); Complement Receptor Type 4
Term UI T489960
Date04/17/2002
LexicalTag NON
ThesaurusID NLM (2003)

Integrin alphaXbeta2 MeSH Descriptor Data 2025