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Membrane Cofactor Protein MeSH Descriptor Data 2025


MeSH Heading
Membrane Cofactor Protein
Tree Number(s)
D12.776.124.486.274.920.124
D12.776.543.750.705.833.124
Unique ID
D051916
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051916
Scope Note
A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.
Entry Term(s)
Antigens, CD46
CD46 Antigen
CD46 Antigens
Trophoblast-Leukocyte Common Antigen
Pharm Action
Immunologic Factors
Public MeSH Note
2018; see ANTIGENS, CD46 1987-2017; MEMBRANE COFACTOR PROTEIN was indexed under MEMBRANE GLYCOPROTEINS 1988-2005; under ANTIGENS, CD 1992-2005; under ANTIGENS, DIFFERENTIATION 1990-1991; and under MEMBRANE PROTEINS 1987
History Note
2018 (1987)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2017/05/24
Membrane Cofactor Protein Preferred
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