MeSH Browser

MeSH Heading: Macrophage-1 Antigen
Tree Number(s): D12.776.543.750.705.408.495.500; D12.776.543.750.705.408.600.500; D12.776.543.750.705.833.500
Unique ID: D016177
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016177
Scope Note: An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
Entry Term(s): Adhesive Receptor Mac-1; CR3 Receptor; Complement 3 Receptor; Integrin alpha(M)beta(2); Integrin alpha-M beta-2; Integrin alphaMbeta2; Mac-1 Adhesive Receptor; Mac-1 Antigen; Mac-1 Receptor; Mo1 Antigen Receptor; Mo1 Glycoprotein Receptor; Receptor, CR3; Receptor, Complement 3; Receptor, Mo1 Antigen; Receptor, Mo1 Glycoprotein
Registry Numbers: 0
Previous Indexing: Antigens, Differentiation (1988-1990); Receptors, Leukocyte-Adhesion (1989-1990)
Public MeSH Note: 91; INTEGRIN ALPHA(M)BETA(2) was indexed under INTEGRINS 1994-95
Online Note: use MACROPHAGE-1 ANTIGEN (NM) to search INTEGRIN ALPHA(M)BETA(2) 1994-95
History Note: 91; INTEGRIN ALPHA(M)BETA(2) was NM 1994-95
Date Established: 1991/01/01
Date of Entry: 1990/04/24
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Integrins [D12.776.543.750.705.408]
        
        Receptors, Fibrinogen [D12.776.543.750.705.408.495]
        
        Macrophage-1 Antigen [D12.776.543.750.705.408.495.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Integrins [D12.776.543.750.705.408]
        
        Receptors, Leukocyte-Adhesion [D12.776.543.750.705.408.600]
        
        Integrin alphaXbeta2 [D12.776.543.750.705.408.600.100]
        
        Lymphocyte Function-Associated Antigen-1 [D12.776.543.750.705.408.600.400]
        
        Macrophage-1 Antigen [D12.776.543.750.705.408.600.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Complement [D12.776.543.750.705.833]
        
        CD11b Antigen [D12.776.543.750.705.833.062]
        
        Membrane Cofactor Protein [D12.776.543.750.705.833.124]
        
        Integrin alphaXbeta2 [D12.776.543.750.705.833.249]
        
        Macrophage-1 Antigen [D12.776.543.750.705.833.500]
        
        Receptor, Anaphylatoxin C5a [D12.776.543.750.705.833.550]
        
        Receptors, Complement 3b [D12.776.543.750.705.833.600]
        
        Receptors, Complement 3d [D12.776.543.750.705.833.610]

Macrophage-1 Antigen Preferred

Concept UI: M0024694
Registry Numbers: 0
Scope Note: An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
Terms: Macrophage-1 Antigen Preferred Term
Term UI T048039
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1991); Integrin alphaMbeta2
Term UI T490201
Date04/19/2002
LexicalTag NON
ThesaurusID NLM (2003); Complement 3 Receptor
Term UI T048034
Date02/15/1990
LexicalTag NON
ThesaurusID NLM (1991); Receptor, Complement 3
Term UI T048035
Date02/15/1990
LexicalTag NON
ThesaurusID NLM (1991); Adhesive Receptor Mac-1
Term UI T048042
Date01/15/1991
LexicalTag NON
ThesaurusID NLM (1992); Mac-1 Adhesive Receptor
Term UI T048043
Date01/15/1991
LexicalTag ACX
ThesaurusID NLM (1992); CR3 Receptor
Term UI T048044
Date01/15/1991
LexicalTag ACX
ThesaurusID NLM (1992); Receptor, CR3
Term UI T048045
Date01/15/1991
LexicalTag ACX
ThesaurusID NLM (1992); Mo1 Antigen Receptor
Term UI T048046
Date01/15/1991
LexicalTag NON
ThesaurusID NLM (1992); Receptor, Mo1 Antigen
Term UI T048047
Date01/15/1991
LexicalTag NON
ThesaurusID NLM (1992); Mo1 Glycoprotein Receptor
Term UI T048048
Date01/15/1991
LexicalTag ACX
ThesaurusID NLM (1992); Receptor, Mo1 Glycoprotein
Term UI T048049
Date01/15/1991
LexicalTag ACX
ThesaurusID NLM (1992); Integrin alpha(M)beta(2)
Term UI T048050
Date04/19/1995
LexicalTag NON
ThesaurusID NLM (1996); Integrin alpha-M beta-2
Term UI T048051
Date01/20/1995
LexicalTag NON
ThesaurusID NLM (1996); Mac-1 Receptor
Term UI T490200
Date04/19/2002
LexicalTag ACX
ThesaurusID NLM (2003); Mac-1 Antigen
Term UI T048038
Date02/15/1990
LexicalTag NON
ThesaurusID NLM (1991)

Macrophage-1 Antigen MeSH Descriptor Data 2025