CD11b Antigen MeSH Descriptor Data 2025

MeSH Heading: CD11b Antigen
Tree Number(s): D09.400.430.890.200.074.750; D12.776.395.550.200.074.750; D12.776.543.550.200.093.750; D12.776.543.750.705.408.100.150; D12.776.543.750.705.833.062; D23.050.301.350.074.049
Unique ID: D039481
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D039481
Scope Note: A CD antigen that contains a conserved integrin I-domain which is involved in ligand binding. When combined with CD18 the two subunits form MACROPHAGE-1 ANTIGEN.
Entry Term(s): Antigens, CD11b; CD11b Antigens; Complement Component Receptor 3, alpha; ITGAM Protein; Integrin alpha M; Integrin alphaM; Mo1 Antigen; Mo1 Glycoprotein; alphaM Integrin
Previous Indexing: Macrophage-1 Antigen (1990-2002)
Public MeSH Note: 2018; see ANTIGENS, CD11B 2003-2017; for ANTIGENS CD11B and CD11B ANTIGEN see MACROPHAGE-1 ANTIGEN 1995-2002; for M01 ANTIGEN & MO1 GLYCOPROTEIN see MACROPHAGE-1 ANTIGEN 1991-2002
History Note: 2018 (1990); for ANTIGENS CD11B and CD11B ANTIGEN use MACROPHAGE-1 ANTIGEN 1995-2002; for M01 ANTIGEN & MO1 GLYCOPROTEIN use MACROPHAGE-1 ANTIGEN 1991-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - Cell Adhesion Molecules [D09.400.430.890.200]
        
        CD11 Antigens [D09.400.430.890.200.074]
        
        CD11a Antigen [D09.400.430.890.200.074.500]
        
        CD11b Antigen [D09.400.430.890.200.074.750]
        
        CD11c Antigen [D09.400.430.890.200.074.875]
        
        Lymphocyte Function-Associated Antigen-1 [D09.400.430.890.200.074.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Cell Adhesion Molecules [D12.776.395.550.200]
        
        CD11 Antigens [D12.776.395.550.200.074]
        
        CD11a Antigen [D12.776.395.550.200.074.500]
        
        CD11b Antigen [D12.776.395.550.200.074.750]
        
        CD11c Antigen [D12.776.395.550.200.074.875]
        
        Lymphocyte Function-Associated Antigen-1 [D12.776.395.550.200.074.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Cell Adhesion Molecules [D12.776.543.550.200]
        
        CD11 Antigens [D12.776.543.550.200.093]
        
        CD11a Antigen [D12.776.543.550.200.093.500]
        
        CD11b Antigen [D12.776.543.550.200.093.750]
        
        CD11c Antigen [D12.776.543.550.200.093.875]
        
        Lymphocyte Function-Associated Antigen-1 [D12.776.543.550.200.093.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Integrins [D12.776.543.750.705.408]
        
        Integrin alpha Chains [D12.776.543.750.705.408.100]
        
        CD11a Antigen [D12.776.543.750.705.408.100.100]
        
        CD11b Antigen [D12.776.543.750.705.408.100.150]
        
        CD11c Antigen [D12.776.543.750.705.408.100.200]
        
        Integrin alpha1 [D12.776.543.750.705.408.100.300]
        
        Integrin alpha2 [D12.776.543.750.705.408.100.350]
        
        Integrin alpha3 [D12.776.543.750.705.408.100.400]
        
        Integrin alpha4 [D12.776.543.750.705.408.100.450]
        
        Integrin alpha5 [D12.776.543.750.705.408.100.500]
        
        Integrin alpha6 [D12.776.543.750.705.408.100.550]
        
        Integrin alphaV [D12.776.543.750.705.408.100.900]
        
        Platelet Membrane Glycoprotein IIb [D12.776.543.750.705.408.100.950]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Complement [D12.776.543.750.705.833]
        
        CD11b Antigen [D12.776.543.750.705.833.062]
        
        Membrane Cofactor Protein [D12.776.543.750.705.833.124]
        
        Integrin alphaXbeta2 [D12.776.543.750.705.833.249]
        
        Macrophage-1 Antigen [D12.776.543.750.705.833.500]
        
        Receptor, Anaphylatoxin C5a [D12.776.543.750.705.833.550]
        
        Receptors, Complement 3b [D12.776.543.750.705.833.600]
        
        Receptors, Complement 3d [D12.776.543.750.705.833.610]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Cell Adhesion Molecules [D23.050.301.350]
      - CD11 Antigens [D23.050.301.350.074]
        
        CD11a Antigen [D23.050.301.350.074.024]
        
        CD11b Antigen [D23.050.301.350.074.049]
        
        CD11c Antigen [D23.050.301.350.074.074]
        
        Lymphocyte Function-Associated Antigen-1 [D23.050.301.350.074.400]

CD11b Antigen Preferred

Concept UI: M0419189
Scope Note: A CD antigen that contains a conserved integrin I-domain which is involved in ligand binding. When combined with CD18 the two subunits form MACROPHAGE-1 ANTIGEN.
Terms: CD11b Antigen Preferred Term
Term UI T048032
Date04/21/1994
LexicalTag NON
ThesaurusID NLM (1995); ITGAM Protein
Term UI T000902564
Date06/10/2016
LexicalTag ACX
ThesaurusID NLM (2017); Integrin alpha M
Term UI T000902565
Date06/10/2016
LexicalTag NON
ThesaurusID NLM (2017); Antigens, CD11b
Term UI T048033
Date04/21/1994
LexicalTag NON
ThesaurusID NLM (1995); Mo1 Antigen
Term UI T048040
Date02/15/1990
LexicalTag NON
ThesaurusID NLM (1991); Mo1 Glycoprotein
Term UI T048041
Date02/15/1990
LexicalTag NON
ThesaurusID NLM (1991); Integrin alphaM
Term UI T488023
Date03/29/2002
LexicalTag NON
ThesaurusID NLM (2003); alphaM Integrin
Term UI T488024
Date03/29/2002
LexicalTag NON
ThesaurusID NLM (2003); Complement Component Receptor 3, alpha
Term UI T000899992
Date04/28/2016
LexicalTag NON
ThesaurusID NLM (2017); CD11b Antigens
Term UI T489985
Date04/18/2002
LexicalTag ACX
ThesaurusID NLM (2003)

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