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An alpha integrin with a molecular weight of 160-kDa that is found in a variety of cell types. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds. Integrin alphaV can combine with several different beta subunits to form heterodimers that generally bind to RGD sequence-containing extracellular matrix proteins.
Entry Term(s)
Antigens, CD51
CD51 Antigen
CD51 Antigens
Integrin alpha V
alpha(V) Integrin
alphav Integrin
Registry Numbers
0
Previous Indexing
Antigens, CD (1994-2002)
Public MeSH Note
2003; INTEGRIN ALPHAV was indexed under ANTIGENS, CD 1994-2002
An alpha integrin with a molecular weight of 160-kDa that is found in a variety of cell types. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds. Integrin alphaV can combine with several different beta subunits to form heterodimers that generally bind to RGD sequence-containing extracellular matrix proteins.