MeSH Browser

MeSH Heading: Integrin alpha5
Tree Number(s): D12.776.543.750.705.408.100.500
Unique ID: D039482
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D039482
Scope Note: This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) that binds FIBRONECTIN and LAMININ. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds.
Entry Term(s): Antigens, CD49e; CD49e Antigen; CD49e Antigens; Integrin alphaF; Platelet Glycoprotein Ic; VLA-5 alpha Chain; alpha(5) Integrin; alpha5 Integrin
Previous Indexing: Antigens, CD (1996-2002)
Public MeSH Note: 2003; INTEGRIN ALPHA5 was indexed under ANTIGENS, CD 1996-2002
History Note: 2003 (1996)
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0247642
Scope Note: This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) that binds FIBRONECTIN and LAMININ. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds.
Terms: Integrin alpha5 Preferred Term
Term UI T277647
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); alpha(5) Integrin
Term UI T277646
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2003); alpha5 Integrin
Term UI T488028
Date03/29/2002
LexicalTag NON
ThesaurusID NLM (2003); Antigens, CD49e
Term UI T489664
Date04/16/2002
LexicalTag ACX
ThesaurusID NLM (2003); CD49e Antigens
Term UI T489665
Date04/16/2002
LexicalTag ACX
ThesaurusID NLM (2003); Platelet Glycoprotein Ic
Term UI T490004
Date04/18/2002
LexicalTag NON
ThesaurusID NLM (2003); Integrin alphaF
Term UI T490005
Date04/18/2002
LexicalTag NON
ThesaurusID NLM (2003); CD49e Antigen
Term UI T277645
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2003); VLA-5 alpha Chain
Term UI T490006
Date04/18/2002
LexicalTag ACX
ThesaurusID NLM (2003)

Integrin alpha5 MeSH Descriptor Data 2025