MeSH Browser

MeSH Heading: Platelet Membrane Glycoprotein IIb
Tree Number(s): D12.776.543.750.705.408.100.950
Unique ID: D040201
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D040201
Scope Note: Platelet membrane glycoprotein IIb is an integrin alpha subunit that heterodimerizes with INTEGRIN BETA3 to form PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX. It is synthesized as a single polypeptide chain which is then postranslationally cleaved and processed into two disulfide-linked subunits of approximately 18 and 110 kDa in size.
Entry Term(s): Antigens, CD41; CD41 Antigen; CD41 Antigens; CD41 Cell Surface Antigen; GP IIb; GPalpha IIb; HUPL-ml Surface Antigen; Integrin alpha IIb; Integrin alphaIIb; Membrane Glycoprotein IIb; Plasma Membrane Glycoprotein IIb
Previous Indexing: Integrins (1992-1995); Platelet Glycoprotein GPIIb-IIIa Complex (1996-2002); Platelet Membrane Glycoproteins (1987-2002)
See Also: Platelet Glycoprotein GPIIb-IIIa Complex
Public MeSH Note: 2003; see PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX 1996-2002
History Note: 2003; use PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX 1996-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Integrins [D12.776.543.750.705.408]
        
        Integrin alpha Chains [D12.776.543.750.705.408.100]
        
        CD11a Antigen [D12.776.543.750.705.408.100.100]
        
        CD11b Antigen [D12.776.543.750.705.408.100.150]
        
        CD11c Antigen [D12.776.543.750.705.408.100.200]
        
        Integrin alpha1 [D12.776.543.750.705.408.100.300]
        
        Integrin alpha2 [D12.776.543.750.705.408.100.350]
        
        Integrin alpha3 [D12.776.543.750.705.408.100.400]
        
        Integrin alpha4 [D12.776.543.750.705.408.100.450]
        
        Integrin alpha5 [D12.776.543.750.705.408.100.500]
        
        Integrin alpha6 [D12.776.543.750.705.408.100.550]
        
        Integrin alphaV [D12.776.543.750.705.408.100.900]
        
        Platelet Membrane Glycoprotein IIb [D12.776.543.750.705.408.100.950]

Platelet Membrane Glycoprotein IIb Preferred

Concept UI: M0028425
Scope Note: Platelet membrane glycoprotein IIb is an integrin alpha subunit that heterodimerizes with INTEGRIN BETA3 to form PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX. It is synthesized as a single polypeptide chain which is then postranslationally cleaved and processed into two disulfide-linked subunits of approximately 18 and 110 kDa in size.
Terms: Platelet Membrane Glycoprotein IIb Preferred Term
Term UI T056831
Date01/20/1995
LexicalTag NON
ThesaurusID NLM (1996); Integrin alpha IIb
Term UI T488002
Date03/29/2002
LexicalTag NON
ThesaurusID NLM (2003); Integrin alphaIIb
Term UI T490104
Date04/18/2002
LexicalTag NON
ThesaurusID NLM (2003); GPalpha IIb
Term UI T490143
Date04/18/2002
LexicalTag NON
ThesaurusID NLM (2003); CD41 Antigen
Term UI T056832
Date03/13/1995
LexicalTag ACX
ThesaurusID NLM (1996); Antigens, CD41
Term UI T056833
Date01/20/1995
LexicalTag ACX
ThesaurusID NLM (1996); CD41 Antigens
Term UI T056834
Date01/20/1995
LexicalTag ACX
ThesaurusID NLM (1996); CD41 Cell Surface Antigen
Term UI T056836
Date12/23/1996
LexicalTag ACX
ThesaurusID NLM (1998); HUPL-ml Surface Antigen
Term UI T056837
Date12/23/1996
LexicalTag NON
ThesaurusID NLM (1998); GP IIb
Term UI T056838
Date01/20/1995
LexicalTag ABB
ThesaurusID NLM (1996); Plasma Membrane Glycoprotein IIb
Term UI T056840
Date01/20/1995
LexicalTag NON
ThesaurusID NLM (1996); Membrane Glycoprotein IIb
Term UI T056839
Date01/20/1995
LexicalTag NON
ThesaurusID NLM (1996)

Platelet Membrane Glycoprotein IIb MeSH Descriptor Data 2025