MeSH Browser

MeSH Heading: CD11c Antigen
Tree Number(s): D09.400.430.890.200.074.875; D09.400.430.890.200.275.500; D12.776.395.550.200.074.875; D12.776.395.550.200.275.500; D12.776.543.550.200.093.875; D12.776.543.550.200.275.500; D12.776.543.750.705.408.100.200; D12.776.543.750.705.408.600.100.500; D12.776.543.750.705.833.249.500; D23.050.301.350.074.074; D23.050.301.350.275.500
Unique ID: D039521
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D039521
Scope Note: An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels on monocytes and combines with CD18 ANTIGEN to form the cell surface receptor INTEGRIN ALPHAXBETA2. The subunit contains a conserved I-domain which is characteristic of several of alpha integrins.
Entry Term(s): Antigens, CD11c; CD11c Antigens; Integrin alphaX; Leu-M5 Antigens
Previous Indexing: Integrin alphaXbeta2 (1995-2002)
Public MeSH Note: 2018; see ANTIGENS, CD11C 2003-2018; for CD11C ANTIGEN and ANTIGENS, CD11C see COMPLEMENT 4-BINDING PROTEIN 1995-2002
History Note: 2018 (1995); for CD11C ANTIGEN and ANTIGENS, CD11C use INTEGRIN ALPHAXBETA2 1995-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - Cell Adhesion Molecules [D09.400.430.890.200]
        
        CD11 Antigens [D09.400.430.890.200.074]
        
        CD11a Antigen [D09.400.430.890.200.074.500]
        
        CD11b Antigen [D09.400.430.890.200.074.750]
        
        CD11c Antigen [D09.400.430.890.200.074.875]
        
        Lymphocyte Function-Associated Antigen-1 [D09.400.430.890.200.074.937]

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - Cell Adhesion Molecules [D09.400.430.890.200]
        
        Integrin alphaXbeta2 [D09.400.430.890.200.275]
        
        CD11c Antigen [D09.400.430.890.200.275.500]
        
        CD18 Antigens [D09.400.430.890.200.275.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Cell Adhesion Molecules [D12.776.395.550.200]
        
        CD11 Antigens [D12.776.395.550.200.074]
        
        CD11a Antigen [D12.776.395.550.200.074.500]
        
        CD11b Antigen [D12.776.395.550.200.074.750]
        
        CD11c Antigen [D12.776.395.550.200.074.875]
        
        Lymphocyte Function-Associated Antigen-1 [D12.776.395.550.200.074.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Cell Adhesion Molecules [D12.776.395.550.200]
        
        Integrin alphaXbeta2 [D12.776.395.550.200.275]
        
        CD11c Antigen [D12.776.395.550.200.275.500]
        
        CD18 Antigens [D12.776.395.550.200.275.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Cell Adhesion Molecules [D12.776.543.550.200]
        
        CD11 Antigens [D12.776.543.550.200.093]
        
        CD11a Antigen [D12.776.543.550.200.093.500]
        
        CD11b Antigen [D12.776.543.550.200.093.750]
        
        CD11c Antigen [D12.776.543.550.200.093.875]
        
        Lymphocyte Function-Associated Antigen-1 [D12.776.543.550.200.093.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Cell Adhesion Molecules [D12.776.543.550.200]
        
        Integrin alphaXbeta2 [D12.776.543.550.200.275]
        
        CD11c Antigen [D12.776.543.550.200.275.500]
        
        CD18 Antigens [D12.776.543.550.200.275.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Integrins [D12.776.543.750.705.408]
        
        Integrin alpha Chains [D12.776.543.750.705.408.100]
        
        CD11a Antigen [D12.776.543.750.705.408.100.100]
        
        CD11b Antigen [D12.776.543.750.705.408.100.150]
        
        CD11c Antigen [D12.776.543.750.705.408.100.200]
        
        Integrin alpha1 [D12.776.543.750.705.408.100.300]
        
        Integrin alpha2 [D12.776.543.750.705.408.100.350]
        
        Integrin alpha3 [D12.776.543.750.705.408.100.400]
        
        Integrin alpha4 [D12.776.543.750.705.408.100.450]
        
        Integrin alpha5 [D12.776.543.750.705.408.100.500]
        
        Integrin alpha6 [D12.776.543.750.705.408.100.550]
        
        Integrin alphaV [D12.776.543.750.705.408.100.900]
        
        Platelet Membrane Glycoprotein IIb [D12.776.543.750.705.408.100.950]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Integrins [D12.776.543.750.705.408]
        
        Receptors, Leukocyte-Adhesion [D12.776.543.750.705.408.600]
        
        Integrin alphaXbeta2 [D12.776.543.750.705.408.600.100]
        
        CD11c Antigen [D12.776.543.750.705.408.600.100.500]
        
        CD18 Antigens [D12.776.543.750.705.408.600.100.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Complement [D12.776.543.750.705.833]
        
        Integrin alphaXbeta2 [D12.776.543.750.705.833.249]
        
        CD11c Antigen [D12.776.543.750.705.833.249.500]
        
        CD18 Antigens [D12.776.543.750.705.833.249.750]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Cell Adhesion Molecules [D23.050.301.350]
      - CD11 Antigens [D23.050.301.350.074]
        
        CD11a Antigen [D23.050.301.350.074.024]
        
        CD11b Antigen [D23.050.301.350.074.049]
        
        CD11c Antigen [D23.050.301.350.074.074]
        
        Lymphocyte Function-Associated Antigen-1 [D23.050.301.350.074.400]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Cell Adhesion Molecules [D23.050.301.350]
      - Integrin alphaXbeta2 [D23.050.301.350.275]
        
        CD11c Antigen [D23.050.301.350.275.500]
        
        CD18 Antigens [D23.050.301.350.275.750]

CD11c Antigen Preferred

Concept UI: M0024680
Scope Note: An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels on monocytes and combines with CD18 ANTIGEN to form the cell surface receptor INTEGRIN ALPHAXBETA2. The subunit contains a conserved I-domain which is characteristic of several of alpha integrins.
Terms: CD11c Antigen Preferred Term
Term UI T048002
Date04/21/1994
LexicalTag ACX
ThesaurusID NLM (1995); Leu-M5 Antigens
Term UI T048000
Date03/28/1994
LexicalTag NON
ThesaurusID NLM (1995); Antigens, CD11c
Term UI T048001
Date04/21/1994
LexicalTag ACX
ThesaurusID NLM (1995); Integrin alphaX
Term UI T488013
Date03/29/2002
LexicalTag NON
ThesaurusID NLM (2003); CD11c Antigens
Term UI T489980
Date04/18/2002
LexicalTag ACX
ThesaurusID NLM (2003)

CD11c Antigen MeSH Descriptor Data 2025