MeSH Browser

MeSH Heading: Integrin alpha4
Tree Number(s): D12.776.543.750.705.408.100.450
Unique ID: D039441
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D039441
Scope Note: An integrin alpha subunit that is unique in that it does not contain an I-domain, and its proteolytic cleavage site is near the middle of the extracellular portion of the polypeptide rather than close to the membrane, as in other integrin alpha subunits.
Entry Term(s): Antigens, CD49d; CD49d Antigen; CD49d Antigens; alpha4 Integrin
Registry Number: 143198-26-9
Previous Indexing: Antigens, CD (1994-2002)
See Also: Natalizumab
Public MeSH Note: 2003; ALPHA4 INTEGRIN (now INTEGRIN ALPHA4) was indexed under ANTIGENS, CD 1994-2002
History Note: 2003 (1994)
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2017/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0228076
Registry Number: 143198-26-9
Scope Note: An integrin alpha subunit that is unique in that it does not contain an I-domain, and its proteolytic cleavage site is near the middle of the extracellular portion of the polypeptide rather than close to the membrane, as in other integrin alpha subunits.
Terms: Integrin alpha4 Preferred Term
Term UI T258080
LexicalTag NON
ThesaurusID NLM (2003); CD49d Antigens
Term UI T489663
Date04/16/2002
LexicalTag ACX
ThesaurusID NLM (2003); Antigens, CD49d
Term UI T489662
Date04/16/2002
LexicalTag ACX
ThesaurusID NLM (2003); CD49d Antigen
Term UI T258079
LexicalTag ACX
ThesaurusID NLM (2003); alpha4 Integrin
Term UI T258081
LexicalTag NON
ThesaurusID NLM (2003)

Integrin alpha4 MeSH Descriptor Data 2023