CD18 Antigens MeSH Descriptor Data 2023

MeSH Heading: CD18 Antigens
Tree Number(s): D12.776.395.550.200.275.750; D12.776.543.550.200.275.750; D12.776.543.750.705.408.200.249; D12.776.543.750.705.408.600.100.750; D12.776.543.750.705.833.249.750; D23.050.301.264.894.118; D23.050.301.350.275.750; D23.101.100.894.118
Unique ID: D018821
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018821
Scope Note: Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE-ADHESION). A defect in the gene encoding CD18 causes LEUKOCYTE-ADHESION DEFICIENCY SYNDROME.
Entry Term(s): Antigens, CD18; CD18 Antigen; Integrin beta2; beta2 Integrin; p150,95 beta-Subunit
Registry Number: 0
Previous Indexing: Antigens, CD (1990-1994); Membrane Glycoproteins (1986-1989); Membrane Proteins (1986-1987); Receptors, Leukocyte-Adhesion (1989-1991)
See Also: Integrin alphaXbeta2; Leukocyte-Adhesion Deficiency Syndrome; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen
Public MeSH Note: 2018; see ANTIGENS, CD18 1995-2017, INTEGRIN BETA2 1994-95, and CD18 ANTIGEN 1986-94; CD18 ANTIGENS was indexed under ANTIGENS, CD 1990-94; RECEPTORS, LEUKOCYTE-ADHESION 1989-91; MEMBRANE GLYCOPROTEINS 1986-89; & MEMBRANE PROTEINS 1986-87; INTEGRIN BETA2 was indexed under INTEGRINS 1994-95
History Note: 2018 (1986)
Date Established: 1995/01/01
Date of Entry: 1994/05/31
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Cell Adhesion Molecules [D12.776.395.550.200]
        
        Integrin alphaXbeta2 [D12.776.395.550.200.275]
        
        CD11c Antigen [D12.776.395.550.200.275.500]
        
        CD18 Antigens [D12.776.395.550.200.275.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Cell Adhesion Molecules [D12.776.543.550.200]
        
        Integrin alphaXbeta2 [D12.776.543.550.200.275]
        
        CD11c Antigen [D12.776.543.550.200.275.500]
        
        CD18 Antigens [D12.776.543.550.200.275.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Integrins [D12.776.543.750.705.408]
        
        Integrin beta Chains [D12.776.543.750.705.408.200]
        
        CD18 Antigens [D12.776.543.750.705.408.200.249]
        
        Integrin beta1 [D12.776.543.750.705.408.200.500]
        
        Integrin beta3 [D12.776.543.750.705.408.200.750]
        
        Integrin beta4 [D12.776.543.750.705.408.200.800]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Integrins [D12.776.543.750.705.408]
        
        Receptors, Leukocyte-Adhesion [D12.776.543.750.705.408.600]
        
        Integrin alphaXbeta2 [D12.776.543.750.705.408.600.100]
        
        CD11c Antigen [D12.776.543.750.705.408.600.100.500]
        
        CD18 Antigens [D12.776.543.750.705.408.600.100.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Complement [D12.776.543.750.705.833]
        
        Integrin alphaXbeta2 [D12.776.543.750.705.833.249]
        
        CD11c Antigen [D12.776.543.750.705.833.249.500]
        
        CD18 Antigens [D12.776.543.750.705.833.249.750]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Antigens, Differentiation [D23.050.301.264]
      - Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
        
        Antigens, CD1 [D23.050.301.264.894.080]
        
        CD2 Antigens [D23.050.301.264.894.090]
        
        CD3 Complex [D23.050.301.264.894.095]
        
        CD4 Antigens [D23.050.301.264.894.100]
        
        CD5 Antigens [D23.050.301.264.894.101]
        
        Antigens, CD7 [D23.050.301.264.894.107]
        
        CD8 Antigens [D23.050.301.264.894.108]
        
        CD13 Antigens [D23.050.301.264.894.113]
        
        CD18 Antigens [D23.050.301.264.894.118]
        
        Lymphocyte Activation Gene 3 Protein [D23.050.301.264.894.121]
        
        Thy-1 Antigens [D23.050.301.264.894.123]
        
        Tumor Necrosis Factor Receptor Superfamily, Member 7 [D23.050.301.264.894.127]
        
        CD28 Antigens [D23.050.301.264.894.128]
        
        CD56 Antigen [D23.050.301.264.894.156]
        
        CD57 Antigens [D23.050.301.264.894.157]
        
        CTLA-4 Antigen [D23.050.301.264.894.158]
        
        Dipeptidyl Peptidase 4 [D23.050.301.264.894.160]
        
        Inducible T-Cell Co-Stimulator Protein [D23.050.301.264.894.580]
        
        Programmed Cell Death 1 Receptor [D23.050.301.264.894.790]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Cell Adhesion Molecules [D23.050.301.350]
      - Integrin alphaXbeta2 [D23.050.301.350.275]
        
        CD11c Antigen [D23.050.301.350.275.500]
        
        CD18 Antigens [D23.050.301.350.275.750]

Biological Factors [D23]
- Biomarkers [D23.101]
  - Antigens, Differentiation [D23.101.100]
    - Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]

CD18 Antigens Preferred

Concept UI: M0028177
Registry Number: 0
Scope Note: Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE-ADHESION). A defect in the gene encoding CD18 causes LEUKOCYTE-ADHESION DEFICIENCY SYNDROME.
Terms: CD18 Antigens Preferred Term
Term UI T056102
Date04/07/1994
LexicalTag NON
ThesaurusID NLM (1995); p150,95 beta-Subunit
Term UI T490161
Date04/18/2002
LexicalTag NON
ThesaurusID NLM (2003); Integrin beta2
Term UI T056104
Date01/25/1995
LexicalTag NON
ThesaurusID NLM (1996); beta2 Integrin
Term UI T056105
Date01/25/1995
LexicalTag NON
ThesaurusID NLM (1996); CD18 Antigen
Term UI T056101
Date04/07/1994
LexicalTag NON
ThesaurusID NLM (1995); Antigens, CD18
Term UI T056103
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1995)

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