MeSH Browser

MeSH Heading: CD28 Antigens
Tree Number(s): D12.776.543.750.705.222.500; D23.050.301.264.894.128; D23.101.100.894.128
Unique ID: D018106
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018106
Scope Note: Costimulatory T-LYMPHOCYTE receptors that have specificity for CD80 ANTIGEN and CD86 ANTIGEN. Activation of this receptor results in increased T-cell proliferation, cytokine production and promotion of T-cell survival.
Entry Term(s): Antigens, CD28; CD28 Antigen; T-Cell-Specific Surface Glycoprotein CD28; TP44 Receptor
Previous Indexing: Antigens, CD (1990-1993); Antigens, Differentiation, T-Lymphocyte (1986-1993)
See Also: B7-1 Antigen
Public MeSH Note: 2018; see ANTIGENS, CD28 1994-2017 and CD28 ANTIGEN 1986-93; CD28 ANTIGENS was indexed under ANTIGENS, CD 1990-93 and ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1986-93
History Note: 2018 (1986)
Date Established: 1994/01/01
Date of Entry: 1993/06/21
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M0027304
Scope Note: Costimulatory T-LYMPHOCYTE receptors that have specificity for CD80 ANTIGEN and CD86 ANTIGEN. Activation of this receptor results in increased T-cell proliferation, cytokine production and promotion of T-cell survival.
Terms: CD28 Antigens Preferred Term
Term UI T054179
Date02/08/1993
LexicalTag ABX
ThesaurusID NLM (1994); TP44 Receptor
Term UI T788045
Date03/30/2011
LexicalTag ABX
ThesaurusID NLM (2012); CD28 Antigen
Term UI T054178
Date02/08/1993
LexicalTag ABX
ThesaurusID NLM (1994); Antigens, CD28
Term UI T054180
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1994); T-Cell-Specific Surface Glycoprotein CD28
Term UI T788044
Date03/30/2011
LexicalTag ABX
ThesaurusID NLM (2012)

CD28 Antigens MeSH Descriptor Data 2025