MeSH Browser

MeSH Heading: Dipeptidyl Peptidase 4
Tree Number(s): D08.811.277.656.350.350.126; D08.811.277.656.959.250; D23.050.301.264.894.160; D23.101.100.894.160
Unique ID: D018819
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018819
Scope Note: A serine protease that catalyses the release of an N-terminal dipeptide. Several biologically-active peptides have been identified as dipeptidyl peptidase 4 substrates including INCRETINS; NEUROPEPTIDES; and CHEMOKINES. The protein is also found bound to ADENOSINE DEAMINASE on the T-CELL surface and is believed to play a role in T-cell activation.
Entry Term(s): Adenosine Deaminase Complexing Protein 2; Antigens, CD26; CD26 Antigen; CD26 Antigens; Dipeptidyl-Peptidase IV
Previous Indexing: Antigens, Differentiation, T-Lymphocyte (1990-1994); Carrier Proteins (1978-1994); Dipeptidyl Peptidases (1980-1994)
Public MeSH Note: 2011; see CD26 ANTIGEN 1995-2010; CD26 ANTIGEN was indexed under ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1990-1994; DIPEPTIDYL PEPTIDASE IV was indexed under DIPEPTIDYL PEPTIDASES 1980-1994
History Note: 2011(1998)
Entry Combination: antagonists & inhibitors:Dipeptidyl-Peptidase IV Inhibitors
Date Established: 1995/01/01
Date of Entry: 1994/05/27
Revision Date: 2017/05/24

Entry Combination: antagonists & inhibitors:Dipeptidyl-Peptidase IV Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0028176
Scope Note: A serine protease that catalyses the release of an N-terminal dipeptide. Several biologically-active peptides have been identified as dipeptidyl peptidase 4 substrates including INCRETINS; NEUROPEPTIDES; and CHEMOKINES. The protein is also found bound to ADENOSINE DEAMINASE on the T-CELL surface and is believed to play a role in T-cell activation.
Terms: Dipeptidyl Peptidase 4 Preferred Term
Term UI T761805
Date12/02/2009
LexicalTag NON
ThesaurusID NLM (2011); Dipeptidyl-Peptidase IV
Term UI T056097
Date04/06/1994
LexicalTag NON
ThesaurusID NLM (1995); CD26 Antigen
Term UI T056098
Date05/25/1994
LexicalTag ACX
ThesaurusID NLM (1995); CD26 Antigens
Term UI T056099
Date04/06/1994
LexicalTag ACX
ThesaurusID NLM (1995); Antigens, CD26
Term UI T056100
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1995); Adenosine Deaminase Complexing Protein 2
Term UI T708156
Date10/22/2007
LexicalTag NON
ThesaurusID NLM (2009)

Dipeptidyl Peptidase 4 MeSH Descriptor Data 2025