NLM Logo

Leukocyte-Adhesion Deficiency Syndrome MeSH Descriptor Data 2025


MeSH Heading
Leukocyte-Adhesion Deficiency Syndrome
Tree Number(s)
C16.320.798.719
C20.673.795.719
Unique ID
D018370
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018370
Scope Note
Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection.
Entry Version
LEUKOCYTE ADHESION DEFIC SYNDROME
Entry Term(s)
Deficiency Syndrome, Leukocyte-Adhesion
Previous Indexing
Immunologic Deficiency Syndromes (1988-1994)
Receptors, Leukocyte-Adhesion/deficiency (1988-1990)
Public MeSH Note
95
History Note
95
Date Established
1995/01/01
Date of Entry
1994/01/25
Revision Date
2019/06/17
Leukocyte-Adhesion Deficiency Syndrome Preferred
page delivered in 0.144s