MeSH Browser

MeSH Heading: Severe Combined Immunodeficiency
Tree Number(s): C16.320.798.750; C16.614.815; C18.452.284.800; C20.673.795.750
Unique ID: D016511
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016511
Scope Note: Group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an X-linked or autosomal recessive defect. Mutations occurring in many different genes cause human Severe Combined Immunodeficiency (SCID).
Entry Version: SEVERE COMBINED IMMUNODEFIC
Entry Term(s): Bare Lymphocyte Syndrome; Immunodeficiency Syndrome, Severe Combined; Immunodeficiency, Severe Combined; Immunologic Deficiency, Severe Combined; Omenn Syndrome; Omenn's Syndrome; Reticuloendotheliosis, Familial; Severe Combined Immune Deficiency; Severe Combined Immunodeficiency Syndrome; Severe Combined Immunologic Deficiency
NLM Classification #: QW 740
Previous Indexing: Immunologic Deficiency Syndromes (1974-1991)
Public MeSH Note: 1992
History Note: 1992
Date Established: 1992/01/01
Date of Entry: 1991/01/03
Revision Date: 2019/06/17

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0025203
Scope Note: Group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an X-linked or autosomal recessive defect. Mutations occurring in many different genes cause human Severe Combined Immunodeficiency (SCID).
Terms: Severe Combined Immunodeficiency Preferred Term
Term UI T049380
Date01/01/1999
LexicalTag NON
ThesaurusID; Immunodeficiency Syndrome, Severe Combined
Term UI T049376
Date10/24/1990
LexicalTag NON
ThesaurusID NLM (1992); Severe Combined Immunodeficiency Syndrome
Term UI T049377
Date10/24/1990
LexicalTag NON
ThesaurusID NLM (1992); Severe Combined Immunologic Deficiency
Term UI T049382
Date10/24/1990
LexicalTag NON
ThesaurusID NLM (1992); Immunologic Deficiency, Severe Combined
Term UI T049381
Date10/24/1990
LexicalTag NON
ThesaurusID NLM (1992); Severe Combined Immune Deficiency
Term UI T000860875
Date06/20/2014
LexicalTag NON
ThesaurusID NLM (2015); Immunodeficiency, Severe Combined
Term UI T049379
Date08/24/1990
LexicalTag NON
ThesaurusID NLM (1992)

Severe Combined Immunodeficiency MeSH Descriptor Data 2023