MeSH Browser

MeSH Heading: Wolman Disease
Tree Number(s): C16.320.565.398.641.201.500; C16.320.565.595.201.500; C16.614.947; C18.452.584.563.641.201.500; C18.452.648.398.641.201.500; C18.452.648.595.201.500
Unique ID: D015223
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015223
Scope Note: The severe infantile form of inherited lysosomal lipid storage diseases due to deficiency of acid lipase (STEROL ESTERASE). It is characterized by the accumulation of neutral lipids, particularly CHOLESTEROL ESTERS in leukocytes, fibroblasts, and hepatocytes. It is also known as Wolman's xanthomatosis and is an allelic variant of CHOLESTEROL ESTER STORAGE DISEASE.
Entry Version: WOLMAN DIS
Entry Term(s): Acid Cholesteryl Ester Hydrolase Deficiency, Wolman Type; Acid Lipase Deficiency; Familial Xanthomatosis; Liposomal Acid Lipase Deficiency, Wolman Type; Wolman's Disease; Xanthomatosis, Familial; Xanthomatosis, Wolman's
Previous Indexing: Cholesterol Esters (1978-1988); Lipase (1966-1988); Lipid Metabolism, Inborn Errors (1966-1988); Lipoidosis (1966-1988); Xanthomatosis (1966-1988)
Public MeSH Note: 1989
History Note: 1989
Date Established: 1989/01/01
Date of Entry: 1988/05/12
Revision Date: 2021/07/01

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0023386
Scope Note: The severe infantile form of inherited lysosomal lipid storage diseases due to deficiency of acid lipase (STEROL ESTERASE). It is characterized by the accumulation of neutral lipids, particularly CHOLESTEROL ESTERS in leukocytes, fibroblasts, and hepatocytes. It is also known as Wolman's xanthomatosis and is an allelic variant of CHOLESTEROL ESTER STORAGE DISEASE.
Terms: Wolman Disease Preferred Term
Term UI T044530
Date01/01/1999
LexicalTag EPO
ThesaurusID; Wolman's Disease
Term UI T044529
Date05/12/1988
LexicalTag EPO
ThesaurusID UNK (19XX); Familial Xanthomatosis
Term UI T842716
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014); Liposomal Acid Lipase Deficiency, Wolman Type
Term UI T645913
Date07/15/2005
LexicalTag EPO
ThesaurusID; Acid Cholesteryl Ester Hydrolase Deficiency, Wolman Type
Term UI T750589
Date05/05/2009
LexicalTag EPO
ThesaurusID; Acid Lipase Deficiency
Term UI T842715
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014); Xanthomatosis, Familial
Term UI T044528
Date05/12/1988
LexicalTag NON
ThesaurusID UNK (19XX); Xanthomatosis, Wolman's
Term UI T044531
Date05/12/1988
LexicalTag EPO
ThesaurusID UNK (19XX)

Wolman Disease MeSH Descriptor Data 2023