NLM Logo

Wolman Disease MeSH Descriptor Data 2025


MeSH Heading
Wolman Disease
Tree Number(s)
C16.320.565.398.641.201.500
C16.320.565.595.201.500
C16.614.947
C18.452.584.563.641.201.500
C18.452.648.398.641.201.500
C18.452.648.595.201.500
Unique ID
D015223
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015223
Scope Note
The severe infantile form of inherited lysosomal lipid storage diseases due to deficiency of acid lipase (STEROL ESTERASE). It is characterized by the accumulation of neutral lipids, particularly CHOLESTEROL ESTERS in leukocytes, fibroblasts, and hepatocytes. It is also known as Wolman's xanthomatosis and is an allelic variant of CHOLESTEROL ESTER STORAGE DISEASE.
Entry Version
WOLMAN DIS
Entry Term(s)
Acid Cholesteryl Ester Hydrolase Deficiency, Type 2
Acid Cholesteryl Ester Hydrolase Deficiency, Wolman Type
Acid Lipase Deficiency
Acid Lipase Disease
Cholesterol ester hydrolase deficiency
Familial Xanthomatosis
LAL Deficiency
LIPA Deficiency
Liposomal Acid Lipase Deficiency, Wolman Type
Lysosomal Acid Lipase Deficiency
Wolman Disease with Hypolipoproteinemia and Acanthocytosis
Wolman's Disease
Xanthomatosis, Familial
Xanthomatosis, Wolman's
Previous Indexing
Cholesterol Esters (1978-1988)
Lipase (1966-1988)
Lipid Metabolism, Inborn Errors (1966-1988)
Lipoidosis (1966-1988)
Xanthomatosis (1966-1988)
Public MeSH Note
1989
History Note
1989
Date Established
1989/01/01
Date of Entry
2024/08/09
Revision Date
2024/06/11
Wolman Disease Preferred
Acid Cholesteryl Ester Hydrolase Deficiency, Type 2 Narrower
page delivered in 0.11s