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Hyper-IgM Immunodeficiency Syndrome MeSH Descriptor Data 2021


MeSH Heading
Hyper-IgM Immunodeficiency Syndrome
Tree Number(s)
C15.378.147.333.249
C16.320.413
C16.320.798.625
C20.673.430.250
C20.673.795.625
Unique ID
D053306
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053306
Scope Note
A rare inherited immunodeficiency syndrome characterized by normal or elevated serum IMMUNOGLOBULIN M levels with absence of IMMUNOGLOBULIN G; IMMUNOGLOBULIN A; and IMMUNOGLOBULIN E. It results in a profound susceptibility to BACTERIAL INFECTIONS and an increased susceptibility to OPPORTUNISTIC INFECTIONS. Several subtypes of hyper-IgM immunodeficiency syndrome exist depending upon the location of genetic mutation.
Entry Term(s)
HIGM2 Syndrome
HIGM3 Syndrome
HIGM5 Syndrome
Hyper-IgM Immunodeficiency Syndrome Type 2
Hyper-IgM Immunodeficiency Syndrome Type 3
Hyper-IgM Immunodeficiency Syndrome Type 5
Hyper-IgM Immunodeficiency Syndrome, Type 2
Hyper-IgM Immunodeficiency Syndrome, Type 3
Hyper-IgM Immunodeficiency Syndrome, Type 5
Hyper-IgM Syndrome
Hyper-IgM Syndrome 2
Hyper-IgM Syndrome 3
Hyper-IgM Syndrome 5
Immunodeficiency with Hyper-IgM Syndrome
Immunodeficiency with Hyper-IgM, Type 2
Immunodeficiency with Hyper-IgM, Type 3
Immunodeficiency with Hyper-IgM, Type 5
Previous Indexing
Immunoglobulin A (1995-2006)
Immunoglobulin E (1995-2006)
Immunoglobulin G (1995-2006)
Immunoglobulin M (1995-2006)
Immunologic Deficiency Syndromes (1995-2006)
Public MeSH Note
2007
History Note
2007
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2019/06/17
Hyper-IgM Immunodeficiency Syndrome Preferred
Hyper-IgM Immunodeficiency Syndrome, Type 5 Narrower
Hyper-IgM Immunodeficiency Syndrome, Type 2 Narrower
Hyper-IgM Immunodeficiency Syndrome, Type 3 Narrower
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