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Donohue Syndrome MeSH Descriptor Data 2023


MeSH Heading
Donohue Syndrome
Tree Number(s)
C05.660.207.325
C16.131.077.313
C16.320.215
C18.452.394.750.654
C19.246.537
Unique ID
D056731
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D056731
Scope Note
Rare autosomal recessive syndrome of extreme insulin resistance due to mutations in the binding domain of INSULIN RECEPTOR. Clinical features include severe intrauterine and postnatal growth restriction, characteristic dysmorphic FACIES; HIRSUTISM; VIRILIZATION; multiple endocrine abnormalities, and early death.
Entry Term(s)
Leprechaunism
Mendenhall Syndrome
Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities
Rabson-Mendenhall Syndrome
Previous Indexing
Abnormalities, Multiple (2002-2009)
Acanthosis Nigricans (2002-2009)
Diabetes Mellitus (2000-2009)
See Also
Insulin Resistance
Receptor, Insulin
Public MeSH Note
2010
History Note
2010
Date Established
2010/01/01
Date of Entry
2009/07/06
Revision Date
2012/07/03
Donohue Syndrome Preferred
Rabson-Mendenhall Syndrome Related
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