MeSH Browser

MeSH Heading: Prader-Willi Syndrome
Tree Number(s): C10.597.606.360.690; C16.131.077.730; C16.131.260.700; C16.320.180.700; C18.654.726.750.500.740
Unique ID: D011218
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011218
Scope Note: An autosomal dominant disorder caused by deletion of the proximal long arm of the paternal chromosome 15 (15q11-q13) or by inheritance of both of the pair of chromosomes 15 from the mother (UNIPARENTAL DISOMY) which are imprinted (GENETIC IMPRINTING) and hence silenced. Clinical manifestations include MENTAL RETARDATION; MUSCULAR HYPOTONIA; HYPERPHAGIA; OBESITY; short stature; HYPOGONADISM; STRABISMUS; and HYPERSOMNOLENCE. (Menkes, Textbook of Child Neurology, 5th ed, p229)
Entry Term(s): Labhart-Willi Syndrome; Labhart-Willi-Prader-Fanconi Syndrome; Prader Labhart Willi Syndrome; Prader-Labhart-Willi Syndrome; Royer Syndrome; Royer's Syndrome; Willi-Prader Syndrome
NLM Classification #: QS 675
Previous Indexing: Abnormalities, Multiple (1968-1976); Carbohydrate Metabolism, Inborn Errors (1969-1976); Hypogonadism (1966-1976); Mental Retardation (1966-1976); Obesity (1966-1976)
See Also: Intellectual Disability
Public MeSH Note: 1977
History Note: 1977
Date Established: 1977/01/01
Date of Entry: 1976/04/13
Revision Date: 2021/07/07

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Prader-Willi Syndrome MeSH Descriptor Data 2023