MeSH Browser

MeSH Heading: Trisomy 18 Syndrome
Tree Number(s): C14.240.400.975; C14.280.400.975; C16.131.077.929; C16.131.240.400.968; C16.131.260.932; C16.320.180.932
Unique ID: D000073842
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000073842
Scope Note: A chromosome disorder associated with TRISOMY of all or part of CHROMOSOME 18. Clinical manifestations include INTRAUTERINE GROWTH RETARDATION; CLEFT PALATE; CONGENITAL HEART DEFECTS; MICROCEPHALY; MICROGNATHIA and clenched fists with overlapping fingers. Most affected fetuses do not survive to birth. Those who survive through their first year often have severe INTELLECTUAL DISABILITY.
Entry Term(s): Complete Trisomy 18 Syndrome; Edwards Syndrome; Mosaic Trisomy 18 Syndrome; Trisomy 18; Trisomy E Syndrome
Public MeSH Note: 2018; TRISOMY 18 was indexed under CHROMOSOMES, HUMAN, PAIR 18; and TRISOMY 2014-2017
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2018/05/23

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Trisomy 18 Syndrome MeSH Descriptor Data 2025