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Proteus Syndrome MeSH Descriptor Data 2022


MeSH Heading
Proteus Syndrome
Tree Number(s)
C04.445.435.500
C04.651.435.500
C05.116.099.750
C05.660.585.620
C16.131.077.740
C16.131.621.585.620
Unique ID
D016715
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016715
Annotation
hamartomas & multiple abnorm; "Proteus" refers to the sea god in Greek mythol who could assume many forms; do not use /‌congen & do not coord with INFANT, NEWBORN, DISEASES
Scope Note
Hamartoneoplastic malformation syndrome of uncertain etiology characterized by partial GIGANTISM of the hands and/or feet, asymmetry of the limbs, plantar hyperplasia, hemangiomas (HEMANGIOMA), lipomas (LIPOMA), lymphangiomas (LYMPHANGIOMA), epidermal NEVI; MACROCEPHALY; cranial HYPEROSTOSIS, and long-bone overgrowth. Joseph Merrick, the so-called "elephant man", apparently suffered from Proteus syndrome and not NEUROFIBROMATOSIS, a disorder with similar characteristics.
Entry Term(s)
Elephant Man Disease
Proteus-Like Syndrome
Previous Indexing
Abnormalities, Multiple (1979-1991)
Neoplasms, Multiple Primary (1986-1991)
Neurofibromatosis 1 (1979-1990)
Public MeSH Note
92
History Note
92
Date Established
1992/01/01
Date of Entry
1991/06/21
Revision Date
2013/07/08
Proteus Syndrome Preferred
Proteus-Like Syndrome Related
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