MeSH Browser

MeSH Heading: Complement C4b
Tree Number(s): D12.776.124.486.274.350.260
Unique ID: D015935
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015935
Scope Note: The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
Entry Term(s): C4b Complement; Complement 4b; Complement Component 4b
Pharm Action: Immunologic Factors
Registry Number: 80295-50-7
CAS Type 1 Name: Complement C4b
Previous Indexing: Complement 4 (1975-1989)
Public MeSH Note: 2006; see COMPLEMENT 4B 1990-2005
History Note: 2006 (1990)
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2005/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Complement C4b MeSH Descriptor Data 2023