MeSH Browser

MeSH Heading: Complement C4
Tree Number(s): D12.776.124.486.274.350
Unique ID: D003181
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003181
Scope Note: A glycoprotein that is important in the activation of CLASSICAL COMPLEMENT PATHWAY. C4 is cleaved by the activated COMPLEMENT C1S into COMPLEMENT C4A and COMPLEMENT C4B.
Entry Term(s): C4 Complement; C4 Complement Component; Complement 4; Complement C4, Precursor; Complement Component 4; Pro-C4; Pro-complement 4
Pharm Action: Immunologic Factors
Previous Indexing: Complement (1968-1974); Protein Binding (1966-1974)
Public MeSH Note: 2006; see COMPLEMENT 4 1978-2005, see COMPLEMENT 1975-1977; COMPLEMENT C4, PRECURSOR was indexed under COMPLEMENT 4 1980-2005
History Note: 2006 (1975)
Date Established: 1978/01/01
Date of Entry: 1974/11/11
Revision Date: 2005/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0004934
Scope Note: A glycoprotein that is important in the activation of CLASSICAL COMPLEMENT PATHWAY. C4 is cleaved by the activated COMPLEMENT C1S into COMPLEMENT C4A and COMPLEMENT C4B.
Terms: Complement C4 Preferred Term
Term UI T622441
Date12/07/2004
LexicalTag NON
ThesaurusID NLM (2006); C4 Complement
Term UI T631377
Date02/23/2005
LexicalTag NON
ThesaurusID NLM (2006); C4 Complement Component
Term UI T622443
Date12/07/2004
LexicalTag NON
ThesaurusID NLM (2006); Complement 4
Term UI T009292
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Complement Component 4
Term UI T622442
Date12/07/2004
LexicalTag NON
ThesaurusID NLM (2006)

Complement C4 MeSH Descriptor Data 2025