- Concept UI
- M0004924
- Registry Numbers
- 0
- Scope Note
- The first complement component to act in the activation of CLASSICAL COMPLEMENT PATHWAY. It is a calcium-dependent trimolecular complex made up of three subcomponents: COMPLEMENT C1Q; COMPLEMENT C1R; and COMPLEMENT C1S at 1:2:2 ratios. When the intact C1 binds to at least two antibodies (involving C1q), C1r and C1s are sequentially activated, leading to subsequent steps in the cascade of COMPLEMENT ACTIVATION.
- Terms
-
Complement C1
Preferred Term
Term UI
T622138
Date12/06/2004
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Complement Component 1
Term UI
T622139
Date12/06/2004
LexicalTag
NON
ThesaurusID
NLM (2006)
-
C1 Complement
Term UI
T631370
Date02/23/2005
LexicalTag
NON
ThesaurusID
NLM (2006)
-
Complement 1
Term UI
T009253
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1975)