- Concept UI
- M0024383
- Registry Numbers
- 0
- Scope Note
- A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the membrane attack complex or MAC.
- Terms
-
Complement Membrane Attack Complex
Preferred Term
Term UI
T047297
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1990)
-
C 5b-9
Term UI
T047302
Date04/18/1989
LexicalTag
NON
ThesaurusID
NLM (1990)
-
C5b-8-poly-C9
Term UI
T620384
Date11/29/2004
LexicalTag
NON
ThesaurusID
NLM (2006)
-
C5b-9
Term UI
T047296
Date04/18/1989
LexicalTag
NON
ThesaurusID
NLM (1990)
-
Complement Complex C5b-9
Term UI
T047299
Date02/16/1990
LexicalTag
NON
ThesaurusID
NLM (1991)
-
Cytolytic Terminal Complement Complex
Term UI
T047300
Date01/14/1991
LexicalTag
NON
ThesaurusID
NLM (1992)
-
Membrane Attack Complex
Term UI
T047298
Date04/18/1989
LexicalTag
NON
ThesaurusID
NLM (1990)
-
Terminal Complement Complex
Term UI
T047301
Date01/14/1991
LexicalTag
NON
ThesaurusID
NLM (1992)