- Concept UI
- M000631735
- Scope Note
- A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.
- Terms
-
Cell Adhesion Molecule-1
Preferred Term
Term UI
T000924639
Date05/16/2017
LexicalTag
NON
ThesaurusID
NLM (2018)
-
CADM1 Protein
Term UI
T000924640
Date05/16/2017
LexicalTag
ABX
ThesaurusID
NLM (2018)
-
IGSF4 Protein
Term UI
T000924661
Date05/16/2017
LexicalTag
ABX
ThesaurusID
NLM (2018)
-
TSLC1 Protein
Term UI
T000924662
Date05/16/2017
LexicalTag
ABX
ThesaurusID
NLM (2018)
-
Tumor Suppressor in Lung Cancer 1 Protein
Term UI
T000924663
Date05/16/2017
LexicalTag
NON
ThesaurusID
NLM (2018)