MeSH Browser

MeSH Heading: Nectins
Tree Number(s): D09.400.430.890.200.123; D12.776.395.550.200.123; D12.776.543.550.200.130; D23.050.301.350.123
Unique ID: D000075983
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000075983
Scope Note: A family of calcium-independent cell adhesion molecules of the immunoglobulin superfamily. They are expressed by most cell types and mediate both homotypic and heterotypic cell-cell adhesion. Nectins function in a variety of morphogenetic and developmental processes that include organogenesis of the eye, ear, tooth, and cerebral cortex; they also play roles in viral infection and cell proliferation.
Entry Term(s): CD111 Antigen; CD112 Antigen; CD113 Antigen; Herpesvirus Entry Mediator C; HevC Protein; Human Poliovirus Receptor Related 1; Nectin; Nectin-1; Nectin-1delta; Nectin-2; Nectin-2alpha; Nectin-2delta; Nectin-2gamma; Nectin-3; Nectin1delta; PVRL1; Poliovirus Receptor-Related Protein 1; Prr1 Protein
Registry Numbers: 0
See Also: Immunoglobulin Domains
Public MeSH Note: 2018; NECTINS was indexed under CELL ADHESION MOLECULES 1999-2018
History Note: 2018 (1999)
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - Cell Adhesion Molecules [D09.400.430.890.200]
        
        12E7 Antigen [D09.400.430.890.200.049]
        
        CD11 Antigens [D09.400.430.890.200.074]
        
        CD24 Antigen [D09.400.430.890.200.098]
        
        CEACAM1 Protein [D09.400.430.890.200.107]
        
        Cell Adhesion Molecule-1 [D09.400.430.890.200.115]
        
        Nectins [D09.400.430.890.200.123]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D09.400.430.890.200.131]
        
        CD146 Antigen [D09.400.430.890.200.170]
        
        Endolyn [D09.400.430.890.200.175]
        
        Cadherin Related Proteins [D09.400.430.890.200.188]
        
        Cadherins [D09.400.430.890.200.200]
        
        Carcinoembryonic Antigen [D09.400.430.890.200.210]
        
        CD4 Immunoadhesins [D09.400.430.890.200.230]
        
        Cell Adhesion Molecules, Neuronal [D09.400.430.890.200.250]
        
        Epithelial Cell Adhesion Molecule [D09.400.430.890.200.263]
        
        Integrin alphaXbeta2 [D09.400.430.890.200.275]
        
        Intercellular Adhesion Molecule-1 [D09.400.430.890.200.450]
        
        Intercellular Adhesion Molecule-3 [D09.400.430.890.200.494]
        
        Junctional Adhesion Molecules [D09.400.430.890.200.537]
        
        Receptors, Lymphocyte Homing [D09.400.430.890.200.625]
        
        Selectins [D09.400.430.890.200.700]
        
        Sialic Acid Binding Ig-like Lectin 2 [D09.400.430.890.200.810]
        
        Vascular Cell Adhesion Molecule-1 [D09.400.430.890.200.920]
        
        Vasodilator-Stimulated Phosphoprotein [D09.400.430.890.200.960]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Cell Adhesion Molecules [D12.776.395.550.200]
        
        12E7 Antigen [D12.776.395.550.200.049]
        
        CD11 Antigens [D12.776.395.550.200.074]
        
        CD24 Antigen [D12.776.395.550.200.098]
        
        CEACAM1 Protein [D12.776.395.550.200.107]
        
        Cell Adhesion Molecule-1 [D12.776.395.550.200.115]
        
        Nectins [D12.776.395.550.200.123]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D12.776.395.550.200.131]
        
        CD146 Antigen [D12.776.395.550.200.170]
        
        Endolyn [D12.776.395.550.200.175]
        
        Cadherin Related Proteins [D12.776.395.550.200.188]
        
        Cadherins [D12.776.395.550.200.200]
        
        Carcinoembryonic Antigen [D12.776.395.550.200.210]
        
        CD4 Immunoadhesins [D12.776.395.550.200.230]
        
        Cell Adhesion Molecules, Neuronal [D12.776.395.550.200.250]
        
        Epithelial Cell Adhesion Molecule [D12.776.395.550.200.263]
        
        Integrin alphaXbeta2 [D12.776.395.550.200.275]
        
        Intercellular Adhesion Molecule-1 [D12.776.395.550.200.450]
        
        Intercellular Adhesion Molecule-3 [D12.776.395.550.200.494]
        
        Junctional Adhesion Molecules [D12.776.395.550.200.537]
        
        Receptors, Lymphocyte Homing [D12.776.395.550.200.625]
        
        Selectins [D12.776.395.550.200.700]
        
        Sialic Acid Binding Ig-like Lectin 2 [D12.776.395.550.200.810]
        
        Vascular Cell Adhesion Molecule-1 [D12.776.395.550.200.920]
        
        Vasodilator-Stimulated Phosphoprotein [D12.776.395.550.200.960]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Cell Adhesion Molecules [D12.776.543.550.200]
        
        12E7 Antigen [D12.776.543.550.200.062]
        
        CD11 Antigens [D12.776.543.550.200.093]
        
        CD24 Antigen [D12.776.543.550.200.124]
        
        CEACAM1 Protein [D12.776.543.550.200.126]
        
        Cell Adhesion Molecule-1 [D12.776.543.550.200.128]
        
        Nectins [D12.776.543.550.200.130]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D12.776.543.550.200.131]
        
        CD146 Antigen [D12.776.543.550.200.140]
        
        Endolyn [D12.776.543.550.200.145]
        
        Cadherins [D12.776.543.550.200.200]
        
        Carcinoembryonic Antigen [D12.776.543.550.200.210]
        
        CD4 Immunoadhesins [D12.776.543.550.200.230]
        
        Cell Adhesion Molecules, Neuronal [D12.776.543.550.200.250]
        
        Epithelial Cell Adhesion Molecule [D12.776.543.550.200.263]
        
        Integrin alphaXbeta2 [D12.776.543.550.200.275]
        
        Intercellular Adhesion Molecule-1 [D12.776.543.550.200.450]
        
        Intercellular Adhesion Molecule-3 [D12.776.543.550.200.494]
        
        Junctional Adhesion Molecules [D12.776.543.550.200.537]
        
        Receptors, Lymphocyte Homing [D12.776.543.550.200.625]
        
        Selectins [D12.776.543.550.200.700]
        
        Sialic Acid Binding Ig-like Lectin 2 [D12.776.543.550.200.810]
        
        Vascular Cell Adhesion Molecule-1 [D12.776.543.550.200.920]
        
        Vasodilator-Stimulated Phosphoprotein [D12.776.543.550.200.960]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Cell Adhesion Molecules [D23.050.301.350]

Nectins Preferred

Nectin-2gamma Narrower

Nectin-3 Narrower

Nectin-1delta Narrower

Nectin-1 Narrower

Concept UI: M0362780
Registry Numbers: 0
Terms: Nectin-1 Preferred Term
Term UI T000924726
Date05/17/2017
LexicalTag NON
ThesaurusID NLM (1999); CD111 Antigen
Term UI T000924727
Date05/17/2017
LexicalTag NON
ThesaurusID NLM (2006); HevC Protein
Term UI T000924728
Date05/17/2017
LexicalTag NON
ThesaurusID NLM (2000); Prr1 Protein
Term UI T000924729
Date05/17/2017
LexicalTag NON
ThesaurusID NLM (2000); Herpesvirus Entry Mediator C
Term UI T000924730
Date05/17/2017
LexicalTag NON
ThesaurusID NLM (2000); Human Poliovirus Receptor Related 1
Term UI T000924731
Date05/17/2017
LexicalTag NON
ThesaurusID NLM (2000); Poliovirus Receptor-Related Protein 1
Term UI T000924732
Date05/17/2017
LexicalTag NON
ThesaurusID NLM (2000); PVRL1
Term UI T422560
Date08/25/2000
LexicalTag ABB
ThesaurusID NLM (2000)

Nectin-2delta Narrower

Nectin-2alpha Narrower

Nectin-2 Narrower

Nectins MeSH Descriptor Data 2025