MeSH Browser

MeSH Heading: Platelet Endothelial Cell Adhesion Molecule-1
Tree Number(s): D09.400.430.890.200.131; D12.776.395.550.200.131; D12.776.543.550.200.131; D23.050.301.264.900.131; D23.050.301.350.131; D23.101.100.900.131
Unique ID: D019408
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019408
Scope Note: A cell adhesion molecule, composed of a series of Ig-like domains, and expressed on virtually all MONOCYTES; PLATELETS; and GRANULOCYTES. PECAM-1 is highly expressed on endothelial cells and concentrated at the junctions between them. It is essential for TRANSENDOTHELIAL MIGRATION of leukocytes and removal of apoptotic cells by PHAGOCYTES.
Entry Term(s): Antigens, CD31; CD31 Antigen; CD31 Antigens; PECAM-1
Registry Numbers: 0
Previous Indexing: Antigens, Differentiation, Myelomonocytic (1990-1996); Cell Adhesion Molecules (1995-1996); Membrane Glycoproteins (1990-1994)
See Also: Immunoglobulin Domains
Public MeSH Note: 2018; see ANTIGENS, CD31 1997-2017 and CD31 ANTIGEN 1990-1996; PLATELET ENDOTHELIAL CELL ADHESION MOLECULE-1 was indexed under CELL ADHESION MOLECULES 1995-96; under ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC 1990-96; and under MEMBRANE GLYCOPROTEINS 1990-94
History Note: 2018 (1990)
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - Cell Adhesion Molecules [D09.400.430.890.200]
        
        12E7 Antigen [D09.400.430.890.200.049]
        
        CD11 Antigens [D09.400.430.890.200.074]
        
        CD24 Antigen [D09.400.430.890.200.098]
        
        CEACAM1 Protein [D09.400.430.890.200.107]
        
        Cell Adhesion Molecule-1 [D09.400.430.890.200.115]
        
        Nectins [D09.400.430.890.200.123]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D09.400.430.890.200.131]
        
        CD146 Antigen [D09.400.430.890.200.170]
        
        Endolyn [D09.400.430.890.200.175]
        
        Cadherin Related Proteins [D09.400.430.890.200.188]
        
        Cadherins [D09.400.430.890.200.200]
        
        Carcinoembryonic Antigen [D09.400.430.890.200.210]
        
        CD4 Immunoadhesins [D09.400.430.890.200.230]
        
        Cell Adhesion Molecules, Neuronal [D09.400.430.890.200.250]
        
        Epithelial Cell Adhesion Molecule [D09.400.430.890.200.263]
        
        Integrin alphaXbeta2 [D09.400.430.890.200.275]
        
        Intercellular Adhesion Molecule-1 [D09.400.430.890.200.450]
        
        Intercellular Adhesion Molecule-3 [D09.400.430.890.200.494]
        
        Junctional Adhesion Molecules [D09.400.430.890.200.537]
        
        Receptors, Lymphocyte Homing [D09.400.430.890.200.625]
        
        Selectins [D09.400.430.890.200.700]
        
        Sialic Acid Binding Ig-like Lectin 2 [D09.400.430.890.200.810]
        
        Vascular Cell Adhesion Molecule-1 [D09.400.430.890.200.920]
        
        Vasodilator-Stimulated Phosphoprotein [D09.400.430.890.200.960]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Cell Adhesion Molecules [D12.776.395.550.200]
        
        12E7 Antigen [D12.776.395.550.200.049]
        
        CD11 Antigens [D12.776.395.550.200.074]
        
        CD24 Antigen [D12.776.395.550.200.098]
        
        CEACAM1 Protein [D12.776.395.550.200.107]
        
        Cell Adhesion Molecule-1 [D12.776.395.550.200.115]
        
        Nectins [D12.776.395.550.200.123]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D12.776.395.550.200.131]
        
        CD146 Antigen [D12.776.395.550.200.170]
        
        Endolyn [D12.776.395.550.200.175]
        
        Cadherin Related Proteins [D12.776.395.550.200.188]
        
        Cadherins [D12.776.395.550.200.200]
        
        Carcinoembryonic Antigen [D12.776.395.550.200.210]
        
        CD4 Immunoadhesins [D12.776.395.550.200.230]
        
        Cell Adhesion Molecules, Neuronal [D12.776.395.550.200.250]
        
        Epithelial Cell Adhesion Molecule [D12.776.395.550.200.263]
        
        Integrin alphaXbeta2 [D12.776.395.550.200.275]
        
        Intercellular Adhesion Molecule-1 [D12.776.395.550.200.450]
        
        Intercellular Adhesion Molecule-3 [D12.776.395.550.200.494]
        
        Junctional Adhesion Molecules [D12.776.395.550.200.537]
        
        Receptors, Lymphocyte Homing [D12.776.395.550.200.625]
        
        Selectins [D12.776.395.550.200.700]
        
        Sialic Acid Binding Ig-like Lectin 2 [D12.776.395.550.200.810]
        
        Vascular Cell Adhesion Molecule-1 [D12.776.395.550.200.920]
        
        Vasodilator-Stimulated Phosphoprotein [D12.776.395.550.200.960]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Cell Adhesion Molecules [D12.776.543.550.200]
        
        12E7 Antigen [D12.776.543.550.200.062]
        
        CD11 Antigens [D12.776.543.550.200.093]
        
        CD24 Antigen [D12.776.543.550.200.124]
        
        CEACAM1 Protein [D12.776.543.550.200.126]
        
        Cell Adhesion Molecule-1 [D12.776.543.550.200.128]
        
        Nectins [D12.776.543.550.200.130]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D12.776.543.550.200.131]
        
        CD146 Antigen [D12.776.543.550.200.140]
        
        Endolyn [D12.776.543.550.200.145]
        
        Cadherins [D12.776.543.550.200.200]
        
        Carcinoembryonic Antigen [D12.776.543.550.200.210]
        
        CD4 Immunoadhesins [D12.776.543.550.200.230]
        
        Cell Adhesion Molecules, Neuronal [D12.776.543.550.200.250]
        
        Epithelial Cell Adhesion Molecule [D12.776.543.550.200.263]
        
        Integrin alphaXbeta2 [D12.776.543.550.200.275]
        
        Intercellular Adhesion Molecule-1 [D12.776.543.550.200.450]
        
        Intercellular Adhesion Molecule-3 [D12.776.543.550.200.494]
        
        Junctional Adhesion Molecules [D12.776.543.550.200.537]
        
        Receptors, Lymphocyte Homing [D12.776.543.550.200.625]
        
        Selectins [D12.776.543.550.200.700]
        
        Sialic Acid Binding Ig-like Lectin 2 [D12.776.543.550.200.810]
        
        Vascular Cell Adhesion Molecule-1 [D12.776.543.550.200.920]
        
        Vasodilator-Stimulated Phosphoprotein [D12.776.543.550.200.960]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Antigens, Differentiation [D23.050.301.264]
      - Antigens, Differentiation, Myelomonocytic [D23.050.301.264.900]
        
        CD68 Molecule [D23.050.301.264.900.023]
        
        Lipopolysaccharide Receptors [D23.050.301.264.900.045]
        
        Lewis X Antigen [D23.050.301.264.900.050]
        
        Platelet Endothelial Cell Adhesion Molecule-1 [D23.050.301.264.900.131]
        
        Sialic Acid Binding Ig-like Lectin 3 [D23.050.301.264.900.565]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Cell Adhesion Molecules [D23.050.301.350]

Biological Factors [D23]
- Biomarkers [D23.101]
  - Antigens, Differentiation [D23.101.100]
    - Antigens, Differentiation, Myelomonocytic [D23.101.100.900]

Platelet Endothelial Cell Adhesion Molecule-1 Preferred

Concept UI: M0028878
Registry Numbers: 0
Scope Note: A cell adhesion molecule, composed of a series of Ig-like domains, and expressed on virtually all MONOCYTES; PLATELETS; and GRANULOCYTES. PECAM-1 is highly expressed on endothelial cells and concentrated at the junctions between them. It is essential for TRANSENDOTHELIAL MIGRATION of leukocytes and removal of apoptotic cells by PHAGOCYTES.
Terms: Platelet Endothelial Cell Adhesion Molecule-1 Preferred Term
Term UI T057880
Date02/23/1996
LexicalTag NON
ThesaurusID NLM (1997); CD31 Antigen
Term UI T057876
Date02/23/1996
LexicalTag NON
ThesaurusID NLM (1997); CD31 Antigens
Term UI T057877
Date02/23/1996
LexicalTag NON
ThesaurusID NLM (1997); Antigens, CD31
Term UI T057878
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1997); PECAM-1
Term UI T057879
Date02/23/1996
LexicalTag ABB
ThesaurusID NLM (1997)

Platelet Endothelial Cell Adhesion Molecule-1 MeSH Descriptor Data 2025