MeSH Browser

MeSH Heading: Transcription Activator-Like Effector Nucleases
Tree Number(s): D08.811.277.352.335.350.850; D12.776.828.300.850
Unique ID: D000069896
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000069896
Scope Note: Artificial nucleases that cleave DNA at a defined distance from specific DNA sequences recognized by TRANSCRIPTION ACTIVATOR-LIKE EFFECTORS. They are composed of an endodeoxyribonuclease fused to DNA-binding domains of the transcription activator-like effectors.
Entry Term(s): Nucleases, Transcription Activator-Like Effector; TALEN; TALENs
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000608253
Scope Note: Artificial nucleases that cleave DNA at a defined distance from specific DNA sequences recognized by TRANSCRIPTION ACTIVATOR-LIKE EFFECTORS. They are composed of an endodeoxyribonuclease fused to DNA-binding domains of the transcription activator-like effectors.
Terms: Transcription Activator-Like Effector Nucleases Preferred Term
Term UI T000884219
Date07/29/2015
LexicalTag NON
ThesaurusID NLM (2017); TALEN
Term UI T000996365
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021); TALENs
Term UI T000884220
Date07/29/2015
LexicalTag ACR
ThesaurusID NLM (2017); Nucleases, Transcription Activator-Like Effector
Term UI T000884221
Date07/29/2015
LexicalTag NON
ThesaurusID NLM (2017)

Transcription Activator-Like Effector Nucleases MeSH Descriptor Data 2025