MeSH Browser

MeSH Heading: Transcription Activator-Like Effectors
Tree Number(s): D12.776.097.890; D12.776.260.755.700; D12.776.930.900.550; D23.946.896.490
Unique ID: D000071336
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071336
Scope Note: Virulence factors of pathogenic plant bacteria, such as XANTHOMONAS species, that bind to specific sequences in the PROMOTER REGIONS of host DNA to induce transcription of specific host genes. Variations in the DNA binding domain of TALE family members account for the variations in DNA specificity. The TALE DNA-binding domains are used in various GENETIC TECHNIQUES by fusing them with various DNA modifying enzymes to detect and manipulate sequence-specific targeted DNA sites.
Entry Term(s): TAL Effector; TAL Effectors; Transcription Activator-Like Effector
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000614172
Scope Note: Virulence factors of pathogenic plant bacteria, such as XANTHOMONAS species, that bind to specific sequences in the PROMOTER REGIONS of host DNA to induce transcription of specific host genes. Variations in the DNA binding domain of TALE family members account for the variations in DNA specificity. The TALE DNA-binding domains are used in various GENETIC TECHNIQUES by fusing them with various DNA modifying enzymes to detect and manipulate sequence-specific targeted DNA sites.
Terms: Transcription Activator-Like Effectors Preferred Term
Term UI T000894609
Date02/03/2016
LexicalTag NON
ThesaurusID NLM (2017); Transcription Activator-Like Effector
Term UI T000997506
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); TAL Effectors
Term UI T000897490
Date03/22/2016
LexicalTag NON
ThesaurusID NLM (2017); TAL Effector
Term UI T000997508
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021)

Transcription Activator-Like Effectors MeSH Descriptor Data 2025