MeSH Browser

MeSH Heading: Gene Products, tat
Tree Number(s): D12.776.260.755.199; D12.776.930.900.199; D12.776.964.900.750.750; D12.776.964.925.984.400
Unique ID: D015696
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015696
Scope Note: Trans-acting transcription factors produced by retroviruses such as HIV. They are nuclear proteins whose expression is required for viral replication. The tat protein stimulates LONG TERMINAL REPEAT-driven RNA synthesis for both viral regulatory and viral structural proteins. Tat stands for trans-activation of transcription.
Entry Term(s): Gene Product, tat; tat Gene Products; tat Protein
Previous Indexing: Transcription Factors (1988-1989)
Public MeSH Note: 91; was see under TRANS-ACTIVATORS 1990
History Note: 91(90); was see under TRANS-ACTIVATORS 1990
Date Established: 1991/01/01
Date of Entry: 1989/07/07
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024076
Scope Note: Trans-acting transcription factors produced by retroviruses such as HIV. They are nuclear proteins whose expression is required for viral replication. The tat protein stimulates LONG TERMINAL REPEAT-driven RNA synthesis for both viral regulatory and viral structural proteins. Tat stands for trans-activation of transcription.
Terms: Gene Products, tat Preferred Term
Term UI T046523
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1990); Gene Product, tat
Term UI T046521
Date04/07/1989
LexicalTag ABX
ThesaurusID NLM (1990); tat Gene Products
Term UI T046522
Date05/18/1989
LexicalTag ABX
ThesaurusID NLM (1990); tat Protein
Term UI T046526
Date05/14/1990
LexicalTag ABX
ThesaurusID NLM (1991)

Gene Products, tat MeSH Descriptor Data 2025