MeSH Browser

MeSH Heading: Gene Products, pol
Tree Number(s): D12.776.775.360; D12.776.964.775.375; D12.776.964.900.750.500; D12.776.964.970.600.850.375
Unique ID: D015684
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015684
Annotation: coord with specific virus (IM)
Scope Note: Retroviral proteins coded by the pol gene. They are usually synthesized as a protein precursor (POLYPROTEINS) and later cleaved into final products that include reverse transcriptase, endonuclease/integrase, and viral protease. Sometimes they are synthesized as a gag-pol fusion protein (FUSION PROTEINS, GAG-POL). Pol is short for polymerase, the enzyme class of reverse transcriptase.
Entry Term(s): Gene Product, pol; pol Gene Products; pol Polyprotein; pol Polyproteins; pol Protein
Previous Indexing: Retroviridae Proteins (1983-1989); Reverse Transcriptase (1977-1989); Viral Proteins (1977-1989)
See Also: Endonucleases; Peptide Hydrolases; RNA-Directed DNA Polymerase
Public MeSH Note: 90
History Note: 90
Date Established: 1990/01/01
Date of Entry: 1989/10/12
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024059
Scope Note: Retroviral proteins coded by the pol gene. They are usually synthesized as a protein precursor (POLYPROTEINS) and later cleaved into final products that include reverse transcriptase, endonuclease/integrase, and viral protease. Sometimes they are synthesized as a gag-pol fusion protein (FUSION PROTEINS, GAG-POL). Pol is short for polymerase, the enzyme class of reverse transcriptase.
Terms: Gene Products, pol Preferred Term
Term UI T046458
Date01/01/1999
LexicalTag ABX
ThesaurusID NLM (1990); pol Polyproteins
Term UI T046460
Date04/04/1989
LexicalTag NON
ThesaurusID NLM (1990); Gene Product, pol
Term UI T046456
Date04/04/1989
LexicalTag NON
ThesaurusID NLM (1990); pol Gene Products
Term UI T046457
Date05/18/1989
LexicalTag NON
ThesaurusID NLM (1990); pol Polyprotein
Term UI T046459
Date02/10/1989
LexicalTag NON
ThesaurusID NLM (1990); pol Protein
Term UI T046461
Date05/14/1990
LexicalTag NON
ThesaurusID NLM (1991)

Gene Products, pol MeSH Descriptor Data 2025