MeSH Browser

MeSH Heading: RNA-Directed DNA Polymerase
Tree Number(s): D08.811.913.696.445.308.300.750; D12.776.964.775.375.750; D12.776.964.900.750.500.750; D12.776.964.970.600.850.375.750
Unique ID: D012194
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012194
Scope Note: An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49.
Entry Term(s): DNA Polymerase, RNA-Directed; RNA Transcriptase; RNA-Dependent DNA Polymerase; Reverse Transcriptase; Revertase
Registry Number: EC 2.7.7.49
CAS Type 1 Name: Deoxynucleotide-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed)
Previous Indexing: DNA Nucleotidyltransferases (1968-1971)
Public MeSH Note: 96; was REVERSE TRANSCRIPTASE 1973-95
History Note: 96; was REVERSE TRANSCRIPTASE 1972-95 (Prov 1972)
Entry Combination: antagonists & inhibitors:Reverse Transcriptase Inhibitors
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/06/22

Entry Combination: antagonists & inhibitors:Reverse Transcriptase Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0018988
Registry Number: EC 2.7.7.49
Scope Note: An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49.
Terms: RNA-Directed DNA Polymerase Preferred Term
Term UI T036296
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1972); Reverse Transcriptase
Term UI T036292
Date04/11/1995
LexicalTag NON
ThesaurusID NLM (1996); RNA Transcriptase
Term UI T036294
Date09/01/1983
LexicalTag NON
ThesaurusID UNK (19XX); DNA Polymerase, RNA-Directed
Term UI T036295
Date04/24/1995
LexicalTag NON
ThesaurusID NLM (1996); RNA-Dependent DNA Polymerase
Term UI T036291
Date03/30/1974
LexicalTag NON
ThesaurusID UNK (19XX); Revertase
Term UI T036293
Date10/26/1981
LexicalTag NON
ThesaurusID UNK (19XX)

RNA-Directed DNA Polymerase MeSH Descriptor Data 2023