Telomerase MeSH Descriptor Data 2025

MeSH Heading: Telomerase
Tree Number(s): D08.811.913.696.445.308.300.750.750; D12.776.157.687.613; D12.776.157.725.500.921; D12.776.660.720.613; D12.776.664.962.500.921
Unique ID: D019098
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019098
Scope Note: An essential ribonucleoprotein reverse transcriptase that adds telomeric DNA to the ends of eukaryotic CHROMOSOMES.
Entry Term(s): Telomerase Catalytic Subunit; Telomerase Reverse Transcriptase; Telomerase Reverse Transcriptase Catalytic Subunit
Related Numbers: EC 2.7.7.49
NLM Classification #: QU 141
Previous Indexing: DNA Nucleotidylexotransferase (1989-1995)
See Also: Telomere Homeostasis
Public MeSH Note: 1996; see DNA NUCLEOTIDYLEXOTRANSFERASE 1989-1995; TELOMERASE REVERSE TRANSCRIPTASE was indexed under DNA-BINDING PROTEINS & TELOMERASE 2000-2006, & under FUNGAL PROTEINS 1997, & under PROTEINS 1997-1999
History Note: 1996(1989); use DNA NUCLEOTIDYLEXOTRANSFERASE 1989-1995
Date Established: 1996/01/01
Date of Entry: 1995/06/05
Revision Date: 2017/06/29

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Phosphotransferases [D08.811.913.696]
      - Nucleotidyltransferases [D08.811.913.696.445]
        
        DNA Nucleotidyltransferases [D08.811.913.696.445.308]
        
        DNA-Directed DNA Polymerase [D08.811.913.696.445.308.300]
        
        RNA-Directed DNA Polymerase [D08.811.913.696.445.308.300.750]
        
        HIV Reverse Transcriptase [D08.811.913.696.445.308.300.750.187]
        
        Telomerase [D08.811.913.696.445.308.300.750.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Poly-ADP-Ribose Binding Proteins [D12.776.157.687]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - RNA-Binding Proteins [D12.776.157.725]
      - Ribonucleoproteins [D12.776.157.725.500]
        
        Heterogeneous-Nuclear Ribonucleoproteins [D12.776.157.725.500.313]
        
        Ribonuclease P [D12.776.157.725.500.625]
        
        Ribonucleoproteins, Small Cytoplasmic [D12.776.157.725.500.750]
        
        Ribonucleoproteins, Small Nuclear [D12.776.157.725.500.875]
        
        RNA-Induced Silencing Complex [D12.776.157.725.500.906]
        
        SS-B Antigen [D12.776.157.725.500.914]
        
        Telomerase [D12.776.157.725.500.921]
        
        Vault Ribonucleoprotein Particles [D12.776.157.725.500.937]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Nuclear Proteins [D12.776.660]
    - Poly-ADP-Ribose Binding Proteins [D12.776.660.720]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Nucleoproteins [D12.776.664]
    - RNA-Binding Proteins [D12.776.664.962]
      - Ribonucleoproteins [D12.776.664.962.500]
        
        Heterogeneous-Nuclear Ribonucleoproteins [D12.776.664.962.500.313]
        
        Ribonuclease P [D12.776.664.962.500.625]
        
        Ribonucleoproteins, Small Cytoplasmic [D12.776.664.962.500.750]
        
        Ribonucleoproteins, Small Nuclear [D12.776.664.962.500.875]
        
        RNA-Induced Silencing Complex [D12.776.664.962.500.906]
        
        SS-B Antigen [D12.776.664.962.500.914]
        
        Telomerase [D12.776.664.962.500.921]
        
        Vault Ribonucleoprotein Particles [D12.776.664.962.500.937]

Telomerase Preferred

Telomerase Catalytic Subunit Narrower

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